249 results found
    1. Ecology

    The cuticular hydrocarbon profiles of honey bee workers develop via a socially-modulated innate process

    Cassondra L Vernier, Joshua J Krupp ... Yehuda Ben-Shahar
    Chemical nestmate recognition in honey bee colonies depends on an innate, socially modulated developmental process.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Tissue-specific mitochondrial HIGD1C promotes oxygen sensitivity in carotid body chemoreceptors

    Alba Timón-Gómez, Alexandra L Scharr ... Andy J Chang
    An atypical configuration of mitochondrial electron transport chain proteins may underlie the exquisite sensitivity of the carotid body to small decreases in oxygen availability.
    1. Evolutionary Biology
    2. Neuroscience

    Divergent sensory investment mirrors potential speciation via niche partitioning across Drosophila

    Ian W Keesey, Veit Grabe ... Bill S Hansson
    Phototaxis and courtship behavioral preferences reflect strong correlation with differences in olfactory and visual nervous system investment across five monophyletic Drosophila species, and could help explain their speciation events.
    1. Cell Biology

    A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage

    Madhuja Samaddar, Jérôme Goudeau ... Cynthia Kenyon
    A whole-genome genetic screen links new aspects of oocyte maturation to proteostasis renewal in the immortal Caenorhabditis elegans germ-cell lineage and reveals similarities to somatic cell maintenance during aging.
    1. Evolutionary Biology
    2. Genetics and Genomics

    The seminal odorant binding protein Obp56g is required for mating plug formation and male fertility in Drosophila melanogaster

    Nora C Brown, Benjamin Gordon ... Mariana Federica Wolfner
    A functional genetics approach reveals a novel role for odorant binding proteins in post-mating processes, with complex mechanisms of evolutionary change across closely related insect species.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Pathogen infection and cholesterol deficiency activate the C. elegans p38 immune pathway through a TIR-1/SARM1 phase transition

    Nicholas D Peterson, Janneke D Icso ... Read Pukkila-Worley
    A phase transition of TIR-1/SARM1 induced by either pathogen or non-pathogen stress potentiates its intrinsic NADase activity, which activates the p38 PMK-1 signaling cascade to induce protective immune defenses in Caenorhabditis elegans intestinal epithelial cells.
    1. Neuroscience

    Species-specific modulation of food-search behavior by respiration and chemosensation in Drosophila larvae

    Daeyeon Kim, Mar Alvarez ... Matthieu Louis
    In naturalistic conditions, larvae of the Drosophila group exhibit species-specific strategies to search for food resources through a primitive form of risk-taking behavior that is controlled by a tradeoff between exploitation and odor-driven exploration.
    1. Cancer Biology

    Arginase 1 is a key driver of immune suppression in pancreatic cancer

    Rosa E Menjivar, Zeribe C Nwosu ... Marina Pasca di Magliano
    Deletion of Arginase 1 in myeloid cells delays tumor formation in pancreatic cancer.
    1. Neuroscience
    2. Physics of Living Systems

    Continuous, long-term crawling behavior characterized by a robotic transport system

    James Yu, Stephanie Dancausse ... Mason Klein
    Drosophila larvae manipulated by an automated system can be observed for 30+ hr, and new analysis methods of long-timescale trajectories reveal behavioral features previously inaccessible, such as a bimodal distribution of thermal navigation efficiency in individual animals.
    1. Neuroscience

    Machine Learning Based Modelling of Human and Insect Olfaction Screens Millions of compounds to Identify Pleasant Smelling Insect Repellents

    Joel Kowalewski, Sean M. Boyle ... Anandasankar Ray
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid

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