Targeting senescent cells in human intervertebral discs, using senotherapeutics, provides a potential therapeutic strategy to prevent or reduce disc degeneration and pain.

Genetic analyses uncovered that the asymmetrically long non-coding RNA cherub is required for brain tumor growth.

RNA decay is used at multiple points in the budding yeast unfolded protein response to regulate its suppression and activation, and possibly its attenuation.

Infection of human cells by influenza A virus induces changes in the alternative splicing of host genes that, in turn, promote viral replication.

A long non-coding RNA molecule called cherub is a driver of tumor development.

The burden of antimicrobial resistance in Thailand is deteriorating over time, and 19,122 deaths in the country in 2010 were excess deaths caused by multidrug-resistant bacterial infection.

Mutations that reduce the functioning of rab7 may underlie the degeneration of sensory and motor nerves in Charcot-Marie-Tooth 2B disease, which suggests increasing endolysosomal function as a therapy.

¹H-Magnetic resonance spectroscopy at 14T reveals a metabolic signature for anti-depressant-like effects of acetyl-L-carnitine in nucleus accumbens of susceptible mouse.

IL-1β release from macrophages might be responsible for the unexplained cone segment loss in retinal degenerative diseases that are associated with subretinal inflammation, such as retinitis pigmentosa or geographic atrophy.

The strain of Phytophthora infestans that caused the Great Famine in the late 1840s was caused by a single genotype that is distinct from, but closely related to, the most prevalent modern genotype.