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Fate-mapping, combined with gain- and loss-of-function approaches, reveal the role of BMP signalling in the spatio-temporal development of the tuberal hypothalamus, a critically important brain region.

A novel mechanism links mechanical signals with the molecular YAP and NOTCH signals operating during developmental myogenesis.

A cell cycle timing mechanism similar to one operating in cultured adult oligodendrocyte progenitor cells controls the growth and patterning of the embryonic chick wing bud.

Multiple levels of gene regulation in the TGFβ signaling pathway mediate the expression of Mmp13, establish species-specific domains of bone resorption, and likely generate evolutionary variation in jaw length.

The generation of phosphoinositide 3,4,5-trisphosphate causes an increase in the number of TRPV1 ion channels and insulin receptors in the plasma membrane.

IL-6 gene and protein expression are rapidly and transiently upregulated in the choroid in response to myopic defocus, as a result of prior form deprivation or treatment with +15 D lenses in a nitric oxide-dependent manner.

Chromatin remodeler Hmga1 has two separable functions in neural crest development, first neural crest specification at the neural plate border and later in Wnt-dependent emigration from the neural tube.

Neural plate border cells co-express neural, neural crest, and placodal transcriptional programs before cell fate decisions occur and are transcriptionally heterogeneous along the antero-posterior and medial-lateral axis.

A near-complete flux balance analysis model of a minimal cell demonstrates the high essentiality of its metabolic genes, agrees well with experimental essentiality data and suggests some further gene removals.

Probe-Seq is a cell type specific bulk RNA sequencing method that can be applied to a wide-ranging tissue types from both vertebrates and invertebrates without genetic labeling.