99 results found
    1. Genetics and Genomics

    ZCWPW1 is recruited to recombination hotspots by PRDM9 and is essential for meiotic double strand break repair

    Daniel Wells et al.
    ZCWPW1 has co-evolved with PRDM9, in particular the PRDM9-SET domain, and although not involved in PRDM9's role in positioning recombination events, it is required for PRDM9's role in pairing chromosomes.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

    Jeannette L Tenthorey et al.
    Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.
    1. Evolutionary Biology

    Behavioural diversity of bonobo prey preference as a potential cultural trait

    Liran Samuni et al.
    Bonobo groups that share overlapping ranging areas and engage in regular social exchange show "behavioural group identity" of hunting techniques in the absence of local ecological variation.
    1. Evolutionary Biology
    Neighboring communities of bonobos hunt different prey species

    Social Learning: Does culture shape hunting behavior in bonobos?

    Andrew Whiten
    New evidence that neighboring communities of bonobos hunt different prey species, despite extensive overlaps in where they live and hunt, is difficult to explain without invoking cultural factors.
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    1. Computational and Systems Biology
    2. Neuroscience

    Dopamine role in learning and action inference

    Rafal Bogacz
    A mathematical model describes the function of dopaminergic neurons in both learning and action planning.
    1. Neuroscience

    Phylogenetic variation in cortical layer II immature neuron reservoir of mammals

    Chiara La Rosa et al.
    The higher amount of cortical immature neurons in brains with expanded neocortices may represent a reservoir of young cells for mammals with reduced neurogenesis.
    1. Neuroscience

    Vestigial auriculomotor activity indicates the direction of auditory attention in humans

    Daniel J Strauss et al.
    Recordings of ear muscles in humans show that ears attempt to pivot in the direction that requires attention.
    1. Genetics and Genomics

    Germline burden of rare damaging variants negatively affects human healthspan and lifespan

    Anastasia V Shindyapina et al.
    Rare highly damaging mutations that are present in most human genomes decrease lifespan and are associated with an earlier onset of chronic diseases.
    1. Developmental Biology

    MicroRNA-934 is a novel primate-specific small non-coding RNA with neurogenic function during early development

    Kanella Prodromidou et al.
    Primate-specific miR-934 mediates neurogenesis and downstream neuronal differentiation processes, modulating the expression of genes associated with the subplate, a region most prominent in primates, emerging during early cortical development.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Plasmodium falciparum translational machinery condones polyadenosine repeats

    Slavica Pavlovic Djuranovic et al.
    Adaptations in protein synthesis and mRNA surveillance machinery enabled the malaria-causing parasite P. falciparum to efficiently and accurately translate long polyA nucleotide runs into long poly-lysine peptides.

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