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Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

UNC119 complexes the microtubule binding CRMP to the cortical Ankyrin to immobilize the microtubule cytoskeleton in Caenorhabditis elegans neurons.

Nanos is required for germline specification by erasure of maternal program in primordial germ cells.

Cellular NAD+ levels change during stage conversion and regulate function of a novel transcription factor that controls developmental switching in the human pathogen Entamoeba histolytica.

Asymmetric segregation of V-ATPase may cause distinct acidification levels in the two daughter cells, enabling asymmetric epigenetic inheritance that specifies their respective life-versus-death fates.

Epidermal cells in vertebrates and invertebrates ensheath portions of somatosensory neurons via a conserved morphogenetic mechanism, and this ensheathment regulates morphogenesis and function of Drosophila nociceptive neurons.

Replication origins are fundamental organizers and regulators of gene activity through embryonic development.

Statistical analysis and LASSO regression modeling provide insights into pathogen-specific host response patterns in cerebrospinal fluid from different disease etiologies to support future classification of pathogen type based on host response patterns in meningitis.

In the pancreas, reciprocal interactions between epithelial cells and myeloid cells determine the balance between tissue repair and carcinogenesis by regulating acinar cell plasticity through differential activation of EGFR/MAPK signaling.

Allorecognition in Neurospora crassa requires CWR-1 (cell wall remodeling protein), an essential process that ensures identity of an interconnected fungal syncytial colony and requires the CWR-1 polysaccharide monooxygenase domain, but not its catalytic activity.