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    1. Immunology and Inflammation

    Developing a multivariate prediction model of antibody features associated with protection of malaria-infected pregnant women from placental malaria

    Elizabeth H Aitken, Timon Damelang ... Stephen J Rogerson
    Machine learning identified six protective antibody features and showed for the first time that serological markers can predict protection from placental-malaria, which is important for evaluation and development of vaccines.
    1. Plant Biology

    Natural variation in salt-induced changes in root:shoot ratio reveals SR3G as a negative regulator of root suberization and salt resilience in Arabidopsis

    Maryam Rahmati Ishka, Hayley Sussman ... Magdalena M Julkowska
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Plant Biology

    Unraveling the role of urea hydrolysis in salt stress response during seed germination and seedling growth in Arabidopsis thaliana

    Yuanyuan Bu, Xingye Dong ... Shenkui Liu
    Salt stress triggers excessive hydrolysis of arginine-derived urea in Arabidopsis thaliana, raising cytoplasmic pH and inhibiting seed germination and seedling growth, providing new insights into the relationship between seed nitrogen mobilization and seed germination inhibition.
    1. Developmental Biology
    2. Plant Biology

    Integration of light and metabolic signals for stem cell activation at the shoot apical meristem

    Anne Pfeiffer, Denis Janocha ... Jan U Lohmann
    TOR kinase guides the transition of plant stem cells from the dormant embryonic state to the active adult state by integrating light and metabolic signals.
    1. Epidemiology and Global Health

    Science Forum: Unit of analysis issues in laboratory-based research

    Nick R Parsons, M Dawn Teare, Alice J Sitch
    A simulation study is used to demonstrate how mistakes in identifying the experimental unit and the unit of analysis can lead to incorrect analyses and inappropriate inferences when reporting research studies.
    1. Evolutionary Biology
    2. Plant Biology

    Positive selection and relaxed purifying selection contribute to rapid evolution of male-biased genes in a dioecious flowering plant

    Lei Zhao, Wei Zhou ... Hong-Tao Li
    Computational analyses, for the first time in plants, reveal how male-biased genes evolve faster than female-biased and unbiased genes.
    1. Cell Biology
    2. Plant Biology

    Stromule extension along microtubules coordinated with actin-mediated anchoring guides perinuclear chloroplast movement during innate immunity

    Amutha Sampath Kumar, Eunsook Park ... Jeffrey Lewis Caplan
    Stromules induced during plant innate immunity dynamically interact and use the cytoskeleton to form and to direct the movement of chloroplasts.
    1. Plant Biology

    Plant Arbovirus Mobilizes a Vector Salivary Protein to Initiate Plant Infection

    Jing Zhao, Jie Yang ... Lili Zhang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Compelling
    • Inadequate
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Vicia faba SV channel VfTPC1 is a hyperexcitable variant of plant vacuole Two Pore Channels

    Jinping Lu, Ingo Dreyer ... Rainer Hedrich
    Polymorphic residues of a vacuolar Ca2+ sensor site in TPC1 channels differ between species of Brassicacea and Fabaceae and lead to distinct TPC1 gating behavior.
    1. Plant Biology

    Shade-induced nuclear localization of PIF7 is regulated by phosphorylation and 14-3-3 proteins in Arabidopsis

    Xu Huang, Qian Zhang ... Lin Li
    A phosphorylation dependent translocation of PIF7 and involvement of 14-3-3 proteins reveal novel regulation mechanisms in shade signal transduction.