11,239 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Uncovering the computational mechanisms underlying many-alternative choice

    Armin W Thomas, Felix Molter, Ian Krajbich
    A comparison of different computational models reveals that looking behavior, during value-based choices from 9, 16, 25, or 36 snack foods, actively influences the subjective values of the available alternatives.
    1. Genetics and Genomics

    Drosophila serotonin 2A receptor signaling coordinates central metabolic processes to modulate aging in response to nutrient choice

    Yang Lyu, Kristina J Weaver ... Scott D Pletcher
    Dietary choice per se is sufficient to modulate aging in Drosophila and through serotonergic control of peripheral metabolism.
    1. Evolutionary Biology

    Microstructural and crystallographic evolution of palaeognath (Aves) eggshells

    Seung Choi, Mark E Hauber ... David J Varricchio
    The eggshells of palaeognath birds (e.g. ostrich, moa, kiwi, emu) have diverse homology and convergent features, and are useful modern analogues for the evolution of non-avian dinosaur eggshells.
    1. Neuroscience

    Stimulus-dependent relationships between behavioral choice and sensory neural responses

    Daniel Chicharro, Stefano Panzeri, Ralf M Haefner
    New stimulus-dependencies of choice-related signals in sensory neurons uncovered by new analytical results and methods.
    1. Neuroscience

    Choice history biases subsequent evidence accumulation

    Anne E Urai, Jan Willem de Gee ... Tobias H Donner
    Choice history signals bias the interpretation of current sensory input, akin to shifting endogenous attention toward (or away from) the previously selected interpretation.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Histone H1 prevents non-CG methylation-mediated small RNA biogenesis in Arabidopsis heterochromatin

    Jaemyung Choi, David B Lyons, Daniel Zilberman
    Linker histone H1 and cytosine DNA methylation in contexts other than CG explain patterns of 24 nucleotide small RNA biogenesis in Arabidopsis thaliana.
    1. Cancer Biology

    Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis

    Rohit Singh, Beom K Choi
    When pioneer metastatic cells enter a sentinel lymph node through afferent lymphatics subcapsular sinus, macrophages provide them soil to proliferate and colonize lymph node.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Two locus inheritance of non-syndromic midline craniosynostosis via rare SMAD6 and common BMP2 alleles

    Andrew T Timberlake, Jungmin Choi ... Richard P Lifton
    Epistatic interactions of rare loss of function mutations in SMAD6 and a common variant modifier near BMP2 are the most common cause of midline craniosynostosis in humans.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Heterogeneity of proteome dynamics between connective tissue phases of adult tendon

    Howard Choi, Deborah Simpson ... Chavaunne T Thorpe
    Metabolic labelling reveals complex proteome dynamics in tendon, with faster turnover of proteins in the glycoprotein-rich interfascicular matrix compared to the collagen-rich fascicular matrix.
    1. Ecology
    2. Neuroscience

    Probing the decision-making mechanisms underlying choice between drug and nondrug rewards in rats

    Youna Vandaele, Magalie Lenoir ... Serge H Ahmed
    In a drug choice setting, rats’ preference is initially driven by deliberative processes but shifts to more automatic selection processes after extended training, in accordance with the sequential choice model.

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