59 results found
    1. Neuroscience

    Response repetition biases in human perceptual decisions are explained by activity decay in competitive attractor models

    James J Bonaiuto et al.
    Residual activity from previous trials in a biophysical decision network model causes biases in choice behavior such that a previous response is more likely to be repeated.
    1. Computational and Systems Biology

    Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination

    Fuqing Wu et al.
    A synthetic quadrastable gene network provides a synthetic biology framework to study cell fate determination.
    1. Neuroscience

    Temperature compensation in a small rhythmic circuit

    Leandro M Alonso, Eve Marder
    Computational models demonstrate that circuit resilience to temperature perturbations are associated with smooth transitions between cellular mechanisms as the contributions of different currents are altered while activity is maintained.
    1. Physics of Living Systems
    2. Neuroscience

    Physical limits to magnetogenetics

    Markus Meister
    Recent reports on the ability of biological molecules to sense magnetic fields are found to be inconsistent with basic physical principles.
    1. Neuroscience

    The manifold structure of limb coordination in walking Drosophila

    Brian D DeAngelis et al.
    During walking and turning, the fruit fly Drosophila uses variable limb coordination patterns, which exist on a low-dimensional, continuous manifold.
    1. Structural Biology and Molecular Biophysics

    Regulatory switch at the cytoplasmic interface controls TRPV channel gating

    Lejla Zubcevic et al.
    C-terminal domain of thermoTRPV channels regulates channel gating at the cytoplasmic interface through a switch-like process.
    1. Neuroscience

    Computational modeling of spinal circuits controlling limb coordination and gaits in quadrupeds

    Simon M Danner et al.
    Organization of commissural and long propriospinal neuronal pathways defines gait expression in quadrupeds.
    1. Physics of Living Systems

    Mitigating memory effects during undulatory locomotion on hysteretic materials

    Perrin E Schiebel et al.
    Undulatory animals moving on the surface must manage material memory by either having a slender anatomy that facilitates avoiding previously remodeled substrate, or using waveshapes that effectively utilize the memory.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Microtubules soften due to cross-sectional flattening

    Edvin Memet et al.
    A combination of experiments, theory, and simulations shows that the elastic softening of microtubules when they are bent arises due to the flattening of their tubular cross-section.
    1. Structural Biology and Molecular Biophysics

    Mechanism of activation at the selectivity filter of the KcsA K+ channel

    Florian T Heer et al.
    The transmembrane helices forming the pore determine the conductance of the selectivity filter through allosteric interactions.

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