1,079 results found
    1. Genetics and Genomics

    Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions

    Leslie M Turner, Bettina Harr
    The genomic regions that cause male hybrids between house mouse subspecies to have low fertility have been identified.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Genome rearrangements and pervasive meiotic drive cause hybrid infertility in fission yeast

    Sarah E Zanders et al.
    Rapid acquisition of chromosome rearrangements, together with independently acting transmission distorter alleles on each chromosome, drive near complete sterility in fission yeast hybrids.
    1. Evolutionary Biology

    Genetic transformation of Spizellomyces punctatus, a resource for studying chytrid biology and evolutionary cell biology

    Edgar M Medina et al.
    Spizellomycespunctatusis a genetically tractable chytrid and model organism for comparative cell biology for understanding evolution of the cell cycle, actin dynamics, and cellularization in fungi and early eukaryotes.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Genome mining unearths a hybrid nonribosomal peptide synthetase-like-pteridine synthase biosynthetic gene cluster

    Hyun Bong Park et al.
    A new type of hybrid nonribosomal peptide synthetase (NRPS)-like-pteridine synthase biosynthetic pathway has been illuminated via genome mining.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Modulation of Prdm9-controlled meiotic chromosome asynapsis overrides hybrid sterility in mice

    Sona Gregorova et al.
    Prdm9-generated meiotic asynapsis of homologous chromosomes in mouse subspecific hybrids causes hybrid sterility and can be reversed by introducing random stretches of consubspecific sequence (≥ 27Mb) on four chromosomes most sensitive to asynapsis.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Punctuated evolution and transitional hybrid network in an ancestral cell cycle of fungi

    Edgar M Medina et al.
    Cell cycle network evolution in a fungal ancestor was punctuated by the arrival of a viral DNA-binding protein that was permanently incorporated into the regulatory network controlling cell cycle entry.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Cisplatin-induced DNA double-strand breaks promote meiotic chromosome synapsis in PRDM9-controlled mouse hybrid sterility

    Liu Wang et al.
    The exogenous DNA DSBs improve meiotic chromosome pairing in mouse inter-subspecific hybrids, thus providing an evidence for a DSB-dependent mechanism of the PRDM9-controlled synapsis failure and infertility.
    1. Cell Biology
    2. Immunology and Inflammation

    A two-hybrid antibody micropattern assay reveals specific in cis interactions of MHC I heavy chains at the cell surface

    Cindy Dirscherl et al.
    A generally applicable two-hybrid assay demonstrates that MHC class I heavy chains devoid of beta-2 microglobulin associate within and across allotypes, with implications for endocytosis and autoimmunity.
    1. Chromosomes and Gene Expression

    Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation

    Oscar Velazquez Camacho et al.
    An RNA-mediated mechanism that stabilizes association of the Suv39h enzymes at mouse heterochromatin is defined.
    1. Biochemistry and Chemical Biology
    2. Genetics and Genomics

    Transposase-assisted tagmentation of RNA/DNA hybrid duplexes

    Bo Lu et al.
    Tn5 transposase has direct tagmentation activity towards RNA/DNA hybrids, which is harnessed as a more convenient and faster RNA-seq library construction method and will benefit RNA and chromatin research.

Refine your results by:

Type
Research categories