132 results found
    1. Cell Biology

    A novel biosensor to study cAMP dynamics in cilia and flagella

    Shatanik Mukherjee, Vera Jansen ... Dagmar Wachten
    A new FRET-based cAMP biosensor with nanomolar sensitivity makes it possible to measure cAMP dynamics in miniscule subcellular compartments like cilia and flagella.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Dynamics of the IFT machinery at the ciliary tip

    Alexander Chien, Sheng Min Shih ... Ahmet Yildiz
    During intraflagellar transport (IFT), kinesin-II dissociates from IFT trains at the flagellar tip and its diffusion in flagella serves as a negative feedback mechanism that facilitates flagellar length control in Chlamydomonas.
    1. Structural Biology and Molecular Biophysics

    Three-dimensional flagella structures from animals’ closest unicellular relatives, the Choanoflagellates

    Justine M Pinskey, Adhya Lagisetty ... Daniela Nicastro
    Cryo-electron microscopy reveals previously undescribed structural features of choanoflagellate flagella and provides new insights into flagellar evolution.
    1. Physics of Living Systems

    Length regulation of multiple flagella that self-assemble from a shared pool of components

    Thomas G Fai, Lishibanya Mohapatra ... Ariel Amir
    In the microbe Chlamydomonas reinhardtii, a disassembly rate which depends on flagellar length provides an effective method to regulate the length of its two flagella.
    1. Cell Biology

    Testing the ion-current model for flagellar length sensing and IFT regulation

    Hiroaki Ishikawa, Jeremy Moore ... Wallace F Marshall
    A model for flagellar length control based on calcium influx is rejected based on quantitative measurements in Chlamydomonas cells.
    1. Evolutionary Biology
    2. Physics of Living Systems

    Hydrodynamics of sponge pumps and evolution of the sponge body plan

    Seyed Saeed Asadzadeh, Thomas Kiørboe ... Jens H Walther
    The architecture of flagellated chambers in sponge pumps is linked to that of body plan, supporting the current view that the sponge aquiferous system evolved from an open-type filtration system.
    1. Physics of Living Systems
    2. Cell Biology

    Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella

    Pablo Sartori, Veikko F Geyer ... Jonathon Howard
    The self-organised beat of cilia and flagella is dynamically regulated by curvature.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A model symbiosis reveals a role for sheathed-flagellum rotation in the release of immunogenic lipopolysaccharide

    Caitlin A Brennan, Jason R Hunt ... Edward G Ruby
    Both beneficial and pathogenic bacteria can use their sheathed flagella during host colonization as a novel toxin-/signal-delivery mechanism.
    1. Cell Biology

    The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport

    Diego Huet, Thierry Blisnick ... Philippe Bastin
    A small GTPase within the flagellum can participate in the control of transport from the base to the tip of the flagellum, and back again.
    1. Cell Biology
    2. Evolutionary Biology

    Flagellar energy costs across the tree of life

    Paul E Schavemaker, Michael Lynch
    Prokaryotic and eukaryotic flagella follow a common trend in swimming cost-effectiveness, but eukaryotic flagella are too large for cells with prokaryote volumes, yielding insight into flagellar dissimilarity between taxa.

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