Breane G Budaitis, Shashank Jariwala ... Kristen J Verhey
Force generation by kinesin motor proteins requires formation of both a 2-stranded cover-neck bundle and an asparagine-based latch for transport of membrane-bound cargoes in cells.
Maria Danielle Sallee, Melissa A Pickett, Jessica L Feldman
During intestinal development, apical PAR complex proteins keep apical domains and junctions continuous between cells as they divide and elongate, and ultimately build a continuous functional tube.
June K Corrigan, Deepti Ramachandran ... Alexander S Banks
The metabolic rate of mice is disproportionately affected by the site of experimentation, affecting the phenotypic interpretation of genetically modified strains.
The signaling molecule Frizzled3 plays a part in the development of the nervous system by controlling the ability of motor neurons to form connections with distant target muscles.
Maximilian AH Jakobs, Andrea Dimitracopoulos, Kristian Franze
KymoButler is a machine learning approach towards the reliable, quick, and fully automated analysis of the dynamics of fluorescently labelled particles in living cells.
Nicholas Mikolajewicz, Elizabeth A Zimmermann ... Svetlana V Komarova
Bone cells exposed to physiological forces release ATP through repairable membrane injury, generating an intercellular signal that conveys the destructive potential of forces and the adaptive capacity of endangered cells.