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Novel frequency-based analysis and computation modeling of cilia carpets reveals that tissue-scale metachronal coordination of cilia can arise even in the absence of global synchronization.

Elaborate dendritic branch patterns lead to a local and branch-specific reduction in impedance, which attenuates back-propagating action potentials and limits voltage-gated calcium influx.

Heterogeneity in cytoplasmic calcium concentration alongside B cell activation and differentiation is measured intravitally using an interdisciplinary imaging approach and novel numerical analysis.

Regulation of the endoplasmic reticulum chaperone BiP by calcium.

The primary cilia polycystin proteins, polycystin-1 and polycystin-2, affect cilia length in the kidney collecting duct epithelia, but only polycystin-2 is required for the functional ion channel in this organelle.

Signaling at the primary cilium is important to sustain the morphology, connectivity, and survival of a key neural population within the brain.

Genetic knock-outs of the dynein-2 intermediate chains reveals that both are essential for correct cilia function and transition zone organization, but play different functions in the assembly of dynein-2 motor and in primary cilia formation.

Dynamic calcium activity in the hippocampus changes markedly across behavioral and physiological states and depends on muscarinic acetylcholine receptor activation.

During development, lateral processes of retinal Müller glia are highly motile, and this motility persists when retinal waves and calcium transients are blocked, suggesting that Müller glial morphology is established independent of neuronal activity.

A new open-source computational toolbox for processing in vivo microendoscopic calcium imaging data performs signal demixing and denoising much more accurately than previously available methods, significantly improving the utility of this imaging modality.