263 results found
    1. Neuroscience

    An essential role for MEF2C in the cortical response to loss of sleep in mice

    Theresa E Bjorness et al.
    The transcription factor, MEF2C, mediates a change in approximately one half of the expressed frontal cortical transcriptome controlling cellular metabolism and synaptic strength in response to acute loss of sleep.
    1. Stem Cells and Regenerative Medicine

    Ecdysone steroid hormone remote controls intestinal stem cell fate decisions via the PPARγ-homolog Eip75B in Drosophila

    Lisa Zipper et al.
    A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of Drosophila melanogaster..
    1. Evolutionary Biology
    2. Neuroscience

    Divergent sensory investment mirrors potential speciation via niche partitioning across Drosophila

    Ian W Keesey et al.
    Phototaxis and courtship behavioral preferences reflect strong correlation with differences in olfactory and visual nervous system investment across five monophyletic Drosophila species, and could help explain their speciation events.
    1. Microbiology and Infectious Disease

    Apoptotic neurodegeneration in whitefly promotes the spread of TYLCV

    Shifan Wang et al.
    A plant virus, Tomato yellow leaf curl virus, manipulates the host preference of the vector insect whitefly to promote its transmission by inducing caspase-dependent apoptotic neurodegeneration in vector's brain.
    1. Genetics and Genomics
    2. Neuroscience

    An adipokine feedback regulating diurnal food intake rhythms in mice

    Anthony H Tsang et al.
    Adiponectin signaling integrates metabolic state information to regulate circadian clock function in hypothalamic appetite regulating centers, food intake rhythms, and body weight.
    1. Computational and Systems Biology

    A decentralised neural model explaining optimal integration of navigational strategies in insects

    Xuelong Sun et al.
    The first biology-constrained neural model of insect navigation guidance systems was explained including path integration, visual homing and route following, and their optimal coordination.
    1. Neuroscience

    Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner

    Adam J Granger et al.
    Most ChAT-expressing interneurons are a subset VIP+ interneurons that differentially release GABA and acetylcholine onto different post-synaptic targets, while a separate population of non-VIP ChAT+ neurons release acetylcholine in mPFC.
    1. Neuroscience

    Sleep is bi-directionally modified by amyloid beta oligomers

    Güliz Gürel Özcan et al.
    Amyloid beta, the major component of plaques in Alzheimer's disease, acutely and reversibly signals to modulate sleep as a function of oligomeric length, independently of neuronal loss.
    1. Neuroscience

    Global sleep homeostasis reflects temporally and spatially integrated local cortical neuronal activity

    Christopher W Thomas et al.
    The global sleep homeostatic process tracks sleep-wake history by integrating local cortical neuronal activity over time and space, rather than directly reflecting changes in specific homeostatically regulated physiological variables.
    1. Neuroscience

    Epigenetic inheritance of circadian period in clonal cells

    Yan Li et al.
    Global changes in gene expression associated with differential DNA methylation underlie epigenetic inheritance of circadian periodicity in cells.

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