239 results found
    1. Biophysics and Structural Biology
    2. Plant Biology

    Kinetics of the LOV domain of ZEITLUPE determine its circadian function in Arabidopsis

    Ashutosh Pudasaini et al
    In the plant circadian clock photoreceptor ZEITLUPE, evolutionarily selected residues distinguish photocycle kinetics and allosteric signal transduction pathways to permit proper circadian timing.
    Research Article Updated
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    1. Genes and Chromosomes
    2. Genomics and Evolutionary Biology

    Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

    Jerome S Menet et al
    Genome-wide measurements on mouse liver cells show that transcription, and a particular key transcription factor, have a smaller than expected influence on the mouse circadian system.
    Research Article
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    1. Plant Biology

    PCH1 integrates circadian and light-signaling pathways to control photoperiod-responsive growth in Arabidopsis

    He Huang et al
    A conserved, circadian-regulated protein alters light perception in plants to regulate daily growth in response to changing photoperiod.
    Research Article
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    1. Biophysics and Structural Biology

    Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex

    Shannon N Nangle et al
    X-ray crystallography reveals the structural framework for understanding the function of mammalian transcriptional repression in the cellular circadian clock.
    Research Article Updated
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    1. Cell Biology
    2. Genes and Chromosomes

    Circadian RNA expression elicited by 3’-UTR IRAlu-paraspeckle associated elements

    Manon Torres et al
    Circadian gene expression can be driven by a post-transcriptional mechanism involving circadian mRNA nuclear retention by paraspeckle nuclear bodies.
    Research Article Updated
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    1. Biochemistry
    2. Microbiology and Infectious Disease

    Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway

    Anna M Puszynska, Erin K O'Shea
    The circadian clock of Synechococcus elongatus PCC7942 schedules the activity of the transcription factor RpaA, which controls key events in carbon metabolism that contribute to cell fitness in conditions mimicking the natural environment.
    Short Report
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    1. Neuroscience

    PDF neuron firing phase-shifts key circadian activity neurons in Drosophila

    Fang Guo et al
    A few circadian ‘evening’ neurons within the Drosophila brain play a key role in driving activity as well as keeping time, whereas the well-known PDF-containing morning cells are likely involved in integrating and transmitting light information.
    Research Article Updated
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    1. Genomics and Evolutionary Biology
    2. Neuroscience

    Lhx1 maintains synchrony among circadian oscillator neurons of the SCN

    Megumi Hatori et al
    A transcription factor called Lhx1 coordinates the activity of the brain's master circadian clock, the suprachiasmatic nucleus, by controlling communication between its constituent cells.
    Research Article Updated
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    1. Genomics and Evolutionary Biology
    2. Neuroscience

    Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

    Kazuhiro Shimomura et al
    A gene that codes for a transcription factor that is involved in lipid and carbohydrate metabolism also has a role in the regulation of circadian rhythms.
    Research Article
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    1. Genomics and Evolutionary Biology
    2. Plant Biology

    Natural variation reveals that intracellular distribution of ELF3 protein is associated with function in the circadian clock

    Muhammad Usman Anwer et al
    In Arabidopsis, a natural variant of the ELF3 protein, which originated in Central Asia, is less likely to accumulate in the nucleus, and causes the circadian clock to run faster and be less responsive to environmental cues.
    Research Article Updated
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