246 results found
    1. Cell Biology

    KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism

    Anthony A Ruberto et al.
    Krüppel-like factor 10 coordinates the hepatic circadian transcriptome and protects the liver from the adverse effects of increased sugar consumption.
    1. Neuroscience

    Correction of amblyopia in cats and mice after the critical period

    Ming-fai Fong et al.
    Visual impairment caused by monocular deprivation early in life can be reversed rapidly at older ages by temporarily blocking all activity in the non-deprived eye.
    1. Neuroscience

    Cortical excitability signatures for the degree of sleepiness in human

    Chin-Hsuan Chia et al.
    Patterns of cortical excitability changes reflect the degree of sleepiness in humans.
    1. Developmental Biology
    2. Neuroscience

    Characterization of cephalic and non-cephalic sensory cell types provides insight into joint photo- and mechanoreceptor evolution

    Roger Revilla-i-Domingo et al.
    Molecular, cellular and behavioral genetic approaches in Platynereis dumerilii indicate that r-Opsins can act as ancient, light-dependent modulators of mechanosensation, and suggest that light-independent mechanosensory roles of r-Opsins evolved secondarily.
    1. Cell Biology
    2. Medicine

    Adipocyte NR1D1 dictates adipose tissue expansion during obesity

    Ann Louise Hunter et al.
    Clock protein NR1D1 regulates white adipose tissue expansion and development of obesity-related pathology.
    1. Neuroscience

    A transient postnatal quiescent period precedes emergence of mature cortical dynamics

    Soledad Domínguez et al.
    Maturation of cortical network dynamics is characterized by a nadir that signals the shift from local, loosely correlated, prominently sensory-driven patterns to internally organized, spatially distributed, and temporally precise activity.
    1. Neuroscience

    Conserved visual capacity of rats under red light

    Nader Nikbakht, Mathew E Diamond
    Psychometric measures reveal that, contrary to common assumption, rats have good visual form discrimination capacity under red and even far-red illumination.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    The need for practical insecticide-resistance guidelines to effectively inform mosquito-borne disease control programs

    Alice Namias et al.
    With standardized insecticide-resistance assays failing to inform mosquito-control efficacy due to genotype-by-environment effects, practical resistance monitoring under relevant local conditions is needed to correlate resistance, mosquito-control efficacy, and disease epidemiology.
    1. Neuroscience

    Stability of neocortical synapses across sleep and wake states during the critical period in rats

    Brian A Cary, Gina G Turrigiano
    Sleep and wake states are not sufficient to drive changes in neocortical synaptic strengths.

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