246 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Oxyntomodulin regulates resetting of the liver circadian clock by food

    Dominic Landgraf et al.
    The gut-released peptide oxyntomodulin mediates the alignment of liver clock gene and metabolic transcript rhythms with the timing of food intake by postprandial induction of hepatic Per gene expression.
    1. Genetics and Genomics
    2. Neuroscience

    Usf1, a suppressor of the circadian Clock mutant, reveals the nature of the DNA-binding of the CLOCK:BMAL1 complex in mice

    Kazuhiro Shimomura et al.
    A gene that codes for a transcription factor that is involved in lipid and carbohydrate metabolism also has a role in the regulation of circadian rhythms.
    1. Computational and Systems Biology
    2. Plant Biology

    Coordination of robust single cell rhythms in the Arabidopsis circadian clock via spatial waves of gene expression

    Peter D Gould et al.
    Single cell analysis reveals how period differences between cells and cell-to-cell coupling generates the spatial structure of the plant circadian clock.
    1. Genetics and Genomics
    2. Neuroscience

    An adipokine feedback regulating diurnal food intake rhythms in mice

    Anthony H Tsang et al.
    Adiponectin signaling integrates metabolic state information to regulate circadian clock function in hypothalamic appetite regulating centers, food intake rhythms, and body weight.
    1. Neuroscience

    Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice

    Christian M Gallardo et al.
    For mice, knowing when it is time to feed is dependent on the neurotransmitter dopamine and the D1R receptor of neurons in the dorsal striatum.
    1. Neuroscience

    Loss of ZBTB20 impairs circadian output and leads to unimodal behavioral rhythms

    Zhipeng Qu et al.
    The zinc finger protein ZBTB20 is a morning and evening activity gating factor in mice.
    1. Neuroscience

    Misaligned feeding impairs memories

    Dawn H Loh et al.
    The time at which mice consume food can dramatically affect hippocampal-dependent biochemistry, physiology, and learned behavior.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

    Jerome S Menet et al.
    Genome-wide measurements on mouse liver cells show that transcription, and a particular key transcription factor, have a smaller than expected influence on the mouse circadian system.
    1. Genetics and Genomics
    2. Neuroscience

    Dissection of central clock function in Drosophila through cell-specific CRISPR-mediated clock gene disruption

    Rebecca Delventhal et al.
    Through novel, cell-specific CRISPR tools to disrupt molecular clock genes, it was revealed that circadian rhythms are coordinated through a network, rather than by the clock of 'master regulatory' neurons.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    NRF2 regulates core and stabilizing circadian clock loops, coupling redox and timekeeping in Mus musculus

    Ryan S Wible et al.
    NRF2 is the mechanism through which oxidative signals directly input into the circadian clockwork to link metabolism and timekeeping in Mus musculus.

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