Light-seeking strategies in Zebrafish larvae are dissected using a virtual-reality assay, and these data are used to establish minimal stochastic and neural-circuits models that quantitatively capture this behavior.
Combining spatial restriction of channelrhodopsin to the neuronal cell body with two photon excitation and calcium imaging will enable production of high resolution maps of neural circuitry.
A bright and stochastic multicolor labeling method, Tetbow, facilitates millimeters-scale reconstructions of neuronal circuits at a large scale using tissue clearing.
Automated segmentation of neurons and identification of synapses in electron micrographs is significantly improved by using simple modifications to chemical fixation protocols that preserve extracellular space in the brain.
Input conveying social novelty information from the hypothalamus controls hippocampal activity by recruiting a novel inhibitory circuit in hippocampal area CA2.
Anatomical and physiological analyses identified an inhibitory interneuron that is an integral part of the rod bipolar cell pathway, the circuit for night vision, of the mammalian retina.
The direction-selective circuit in the retina adjusts the contributions of excitatory and inhibitory mechanisms under different stimulus conditions to generate context-dependent neural representations of visual features.
Intracortical circuits in mouse olfactory cortex stabilize odor-evoked activity patterns when upstream inputs, from olfactory bulb, become degraded under anesthesia.
The ability to quickly re-acquire a previously lost motor skill is associated with lasting synaptic changes in the brain circuit that controls that motor skill.
