Interactions in protein complexes can be predicted from evolutionary information from genomic sequences.

The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.

The zebrafish lateral line utilizes multiple, genetically distinct, independently regulated progenitors to generate new hair cells during homeostasis and regeneration, and to maintain progenitor pools.

High-resolution mapping of cohesin-dependent chromatin loops in the genome of budding yeast reveals evolutionarily conserved features for loop formation and cohesin residency as a determinant of loop positioning.

The Spike gene expressed by the vector-based vaccine Vaxzevria bears the risk of cryptic splicing, which in turn may lead to cellular production of soluble, instead of membrane-anchored, Spike protein variants.

CDK9 inhibition in human cells uncovers that Pol II pause duration regulates the frequency of productive transcription initiation.

Proximity biotinylation of the Drosophila centromere suggests a role of RNA helicases, centromeric transcripts, and centromeric R-loops for centromere function.

Controlling cell cycle progression in a developing embryo directly depends on de novo histone supply and a specialized surveillance mechanism for nucleosome assembly.

Circuit transcription factors may define the differentiation and assembly of distinct neurons into functional circuitry.

An array of cytosolic co-chaperones and chaperones helps to maintain newly synthesized mitochondrial outer membrane proteins in an import competent state.