569 results found
    1. Neuroscience

    Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact

    Thomas A Ray, Suva Roy ... Jeremy N Kay
    Selective synapse formation in a retinal motion-sensitive circuit is orchestrated by starburst amacrine cells, which use homotypic interactions to initiate formation of a dendritic scaffold that recruits projections from circuit partners.
    1. Neuroscience

    Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons

    Jason D Vevea, Grant F Kusick ... Edwin R Chapman
    Synaptotagmin 7 is asymmetrically localized to the axonal plasma membrane through γ-secretase processing to promote vesicle docking during short-term synaptic plasticity in mouse hippocampal neurons.
    1. Cancer Biology

    The integration of Tgfβ and Egfr signaling programs confers the ability to lead heterogeneous collective invasion

    Apsra Nasir, Sharon Camacho ... Gray W. Pearson
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Microbiology and Infectious Disease

    Pervasive translation in Mycobacterium tuberculosis

    Carol Smith, Jill G Canestrari ... Joseph T Wade
    Thousands of novel open-reading frames (ORFs) are translated in the bacterium Mycobacterium tuberculosis, including many short ORFs that are likely to contribute to cell fitness.
    1. Biochemistry and Chemical Biology

    A surface proton antenna in carbonic anhydrase II supports lactate transport in cancer cells

    Sina Ibne Noor, Somayeh Jamali ... Holger M Becker
    Carbonic anhydrase II features a surface proton antenna that exclusively mediates proton exchange with monocarboxylate transporters to facilitate proton-coupled lactate transport in cancer cells.
    1. Neuroscience

    Performance in even a simple perceptual task depends on mouse secondary visual areas

    Hannah C Goldbach, Bradley Akitake ... Mark H Histed
    In a simple visual task, that in principle could be performed using information in V1 alone, perturbations of secondary visual areas impair perception.
    1. Cancer Biology
    2. Cell Biology

    A novel L1CAM isoform with angiogenic activity generated by NOVA2-mediated alternative splicing

    Francesca Angiolini, Elisa Belloni ... Claudia Ghigna
    Endothelial cells express a soluble isoform of the L1CAM cell adhesion molecule that is generated by the splicing factor NOVA2 and induces angiogenesis, with relevant implications for ovarian cancer vascularization.
    1. Microbiology and Infectious Disease

    Capsular polysaccharide restrains type VI secretion in Acinetobacter baumannii

    Nicolas Flaugnatti, Loriane Bader ... Melanie Blokesch
    Capsular polysaccharides of Acinetobacter baumannii regulate type VI secretion system activity, balancing self-protection with interbacterial competitiveness.
    1. Cancer Biology
    2. Cell Biology

    A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

    Jesusa Capera, Mireia Pérez-Verdaguer ... Antonio Felipe
    The association of caveolin with the potassium channel Kv1.3 fine-tunes cell survival and apoptosis.
    1. Plant Biology

    CASP microdomain formation requires cross cell wall stabilization of domains and non-cell autonomous action of LOTR1

    Andreas Kolbeck, Peter Marhavý ... Niko Geldner
    Localized lignin impregnations, forming a pan-endodermal net-like diffusion barrier strongly relies on stabilizing signals from neighbors.

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