334 results found
    1. Genetics and Genomics
    2. Immunology and Inflammation

    PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation

    Kenneth T Farabaugh et al.
    Changes in the interactome of the Rel family of transcription factors control adaptation to the environmental stress of hyperosmolarity and determine cell fate.
    1. Evolutionary Biology

    The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts

    Patric M Vaelli et al.
    Skin-associated bacteria underlie the production of a potent defensive neurotoxin in newts, impacting host physiology, molecular evolution, and predator-prey interactions in a coevolutionary arms race.
    1. Microbiology and Infectious Disease

    An atypical DYRK kinase connects quorum-sensing with posttranscriptional gene regulation in Trypanosoma brucei

    Mathieu Cayla et al.
    A trypanosome DYRK kinase that exhibits fundamental differences to conventional DYRK family regulation links parasite quorum sensing, signal transduction and developmental gene expression.
    1. Ecology
    2. Plant Biology

    Determining the scale at which variation in a single gene changes population yields

    Erica McGale et al.
    Variation in the gene NaMPK4 in plant populations increases reproductive yield, an effect which appears to be independent of soil water availability, neighbor-scale interactions and associations with arbuscular mycorrhizal fungi.
    1. Computational and Systems Biology
    2. Neuroscience

    Selectivity to approaching motion in retinal inputs to the dorsal visual pathway

    Todd R Appleby, Michael B Manookin
    Cells in the primate retina show unexpected sensitivity to approaching motion and optical flow.
    1. Neuroscience

    Contextual and cross-modality modulation of auditory cortical processing through pulvinar mediated suppression

    Xiao-lin Chou et al.
    Electrophysiological recording and optogenetic manipulation approaches reveal that a multisensory bottom-up SC-LP-A1 pathway plays a role in contextual and cross-modality modulation of auditory cortical processing.
    1. Neuroscience

    Short-term modulation of the lesioned language network

    Gesa Hartwigsen et al.
    Virtual lesions of the left posterior inferior frontal gyrus in patients with lesions in the left temporo-parietal cortex disrupt phonologial decisions and lead to compensatory upregulation of the lesion homologue.
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Adaptation of hydroxymethylbutenyl diphosphate reductase enables volatile isoprenoid production

    Mareike Bongers et al.
    Differences in HDR product preference present a novel mechanism in plants to control substrate availability for short- and long-chain isoprenoids.
    1. Neuroscience

    Postural control of arm and fingers through integration of movement commands

    Scott T Albert et al.
    After a movement, the final posture of the arm is stabilized by a subcortical structure that mathematically integrates movement commands over time.

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