216 results found
    1. Neuroscience

    Stereotyped transcriptomic transformation of somatosensory neurons in response to injury

    Minh Q Nguyen et al.
    Peripheral injury induces a programmed but reversible transformation of gene expression in somatosensory neurons providing a mechanism to regulate sensory input during wound healing.
    1. Neuroscience

    A connectional hub in the rostral anterior cingulate cortex links areas of emotion and cognitive control

    Wei Tang et al.
    A hub in the rostral anterior cingulate cortex receives unusually high and functionally diverse inputs, providing a biological interface between motivation, incentive based learning, and decision making.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Ancient origins of arthropod moulting pathway components

    André Luiz de Oliveira et al.
    Evolutionary reconstruction of the ecdysis pathway shows that its major elements are present in the majority of metazoans, providing evidence that they originated much earlier than currently assumed.
    1. Neuroscience

    The recovery of standing and locomotion after spinal cord injury does not require task-specific training

    Jonathan Harnie et al.
    Restoring locomotion after complete spinal cord injury does not require locomotor training, only the return of sufficient excitability within neurons of the spinal cord.
    1. Neuroscience

    Pre-saccadic remapping relies on dynamics of spatial attention

    Martin Szinte et al.
    To see the world stable across saccades, the brain compensates retinal shifts induced by the movements, pre-saccadic maps of sensitivity reveal that this process takes time and follows attentional dynamics.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Polo-like kinase Cdc5 regulates Spc72 recruitment to spindle pole body in the methylotrophic yeast Ogataea polymorpha

    Hiromi Maekawa et al.
    Cdc5-dependent SPB regulation is linked to delayed cytoplasmic microtubule organization in Ogataea polymorpha.
    1. Computational and Systems Biology
    2. Developmental Biology

    Elastic force restricts growth of the murine utricle

    Ksenia Gnedeva et al.
    Computational modeling and molecular-biological analysis reveal the role of mechanical force and downstream Yap signaling in growth control during the development and regeneration of sensory epithelium of the inner ear.
    1. Neuroscience

    Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves

    Miriam Schwalm et al.
    Locally recorded calcium events related to slow wave activity show a global cortical fMRI BOLD correlate, establishing a direct relation between a basic neurophysiological signal and the macroscopic perspective of pre-clinical fMRI.
    1. Cell Biology

    A novel mode of capping protein-regulation by twinfilin

    Adam B Johnston et al.
    Twinfilin functions as a pro-capping ligand of capping protein, dynamically competing with inhibitory ligands of capping proteinto control cellular actin assembly.
    1. Neuroscience

    Risk of punishment influences discrete and coordinated encoding of reward-guided actions by prefrontal cortex and VTA neurons

    Junchol Park, Bita Moghaddam
    Risk of punishment during reward seeking behavior is associated with a functional "disconnection" of the PFC-VTA circuit due to a transient loss of VTA-driven theta oscillation.

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