Comparative analysis establishes genetic links among angioimmunoblastic T-cell lymphoma (AITL), clonal hematopoiesis, and concomitant hematologic malignancies, and provides insights into the cell of origin, etiology, and biomarker discovery for AITL.

High degree of clonal persistence and excess of inter-individual convergence are observed in human memory B cell repertoires, along with signatures of both negative and positive selection in most abundant clonal lineages.

Lineage resolved single-cell RNA-seq of mammary carcinoma models uncovers a metabolic vulnerability of taxane-resistant clones.

Just 2-4 follicle stem cells maintain each follicle epithelium in the Drosophila ovary, and they reside within a single ring at the anterior edge of the tissue.

If CHIP and mLOY do not significantly contribute to inflammation, atherosclerosis or myocardial infarction risk independently, CHIP may increase the risk of MI in men who do not carry mLOY.

The dorsal telencephalon (pallium) in medaka fish accommodates an epigenetically distinct brain area that selectively regulates unique set of synaptic genes compared to the surrounding pallial region, providing insights into the evolution of the pallium in vertebrate.

3D niche topology imposes a spatially biased random stem cell loss, which is differentially fine-tuned in neural retina and retinal pigmented epithelium to regulate growth, shape, and cellular topology.

As the first to track clonal evolution from precancerous to metastatic lesions in gallbladder cancer patients, spatial and temporal analyses reveal how subclonal diversity in precancerous stage changes toward the metastasis, which help early detection and effective treatment of cancer.

The rapid development of immune memory in infancy shapes the composition of T cell defenses throughout the human lifespan.

For many bacterial species, recombination dominates genome evolution and phylogenetic patterns that have so far been assumed to reflect clonal relationships, in fact reflect variation in recombination rates across lineages.