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Imaging experiments and simulations reveal that the biophysical mechanism for force generation needed to engulf a forespore is based on coordinated cell wall synthesis and degradation.

The absolute affinities of thousands of variant antibodies are measured in parallel using a combination of cell sorting and high-throughput DNA sequencing.

A systematic optimization of intestinal digestion protocols allows for the isolation and high-dimensional flow cytometric analysis of intestinal immune cells during murine helminth infection.

Rapid yet comprehensive, genome-resolved analysis of fecal samples from premature infants reveals little overlap in strain composition of gut microbial communities, despite co-hospitalization, and suggests the existence of barriers to strain dispersal.

Brain region-specific profiling of O-GlcNAcylation interactome in Drosophila mushroom body suggests that hypo-O-GlcNAcylation impacts cognitive function by regulating translational activity.

An unbiased mutational screen decodes the molecular basis of phage receptor interactions, identifies key functional regions determining activity and host range, and demonstrates the potential for engineering therapeutic phages.

A multi-cohort analysis of 2,500 gut microbiomes and five major diseases discovers that disease-microbiome associations display specific age-centric trends, with diseases characterized by age-centric trends of species gain/loss.

Disturbing the microbiota with antibiotics alters gut redox state via changes in electron acceptor availability, setting the stage for post-antibiotic succession.

Resetting a young gut microbiota in middle-aged individuals extends life span and slows aging in the naturally short-lived turquoise killifish, a new vertebrate model organism to study how the microbiota affects the aging process.