1,543 results found
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Epistasis and entrenchment of drug resistance in HIV-1 subtype B

    Avik Biswas et al.
    Drug resistance in HIV is the result of mutations, which affect fitness depending on epistatic interactions with the entire sequence background that varies within and between patient populations.
    1. Physics of Living Systems

    Phylodynamic theory of persistence, extinction and speciation of rapidly adapting pathogens

    Le Yan et al.
    A model of pathogen co-evolving with host population continuously acquiring immunity is used to identify evolutionary parameters allowing pathogen population to persist without going extinct or splitting into independent lineages.
    1. Human Biology and Medicine
    2. Neuroscience

    Obesity: The emerging neurobiology of calorie addiction

    Cristina García-Cáceres, Matthias H Tschöp
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    1. Evolutionary Biology

    Experimental Evolution: A sticky solution

    David Gresham
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    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: Advancing biology through a deeper understanding of zebrafish ecology and evolution

    David M Parichy
    The zebrafish is a premier model organism for biomedical research, with a rich array of tools and genomic resources, and combining these with a fuller appreciation of wild zebrafish ecology could greatly extend its utility in biological research.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Bacterial Evolution: The road to resistance

    Devon M Fitzgerald
    The way that bacteria grow—either floating in liquid or attached to a surface—affects their ability to evolve antimicrobial resistance and our ability to treat infections.
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    1. Neuroscience

    Serial Behaviour: What can fruit flies teach us about karate?

    Helen H Yang, Thomas R Clandinin
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