6,138 results found
    1. Chromosomes and Gene Expression

    Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

    Dawn Z Eichenfield, Ty Dale Troutman ... Christopher K Glass
    Combinatorial signaling leads to transcription factor co-localization at Rev-erb sensitive enhancers, enabling a diversified cellular response to complex stimuli.
    1. Cell Biology

    An optimized method for 3D fluorescence co-localization applied to human kinetochore protein architecture

    Aussie Suzuki, Sarah K Long, Edward D Salmon
    An optimized 3D fluorescence co-localization method is a useful toolkit to obtain cellular 3D separations between green and red labeled protein domains with nanometer-scale accuracy using light microscopy.
    1. Cancer Biology
    2. Cell Biology

    Regulation of localization and function of the transcriptional co-activator YAP by angiomotin

    Susana Moleirinho, Sany Hoxha ... Joseph L Kissil
    Phosphorylation of Angiomotin regulates YAP localization and activity.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Self-organised segregation of bacterial chromosomal origins

    Andreas Hofmann, Jarno Mäkelä ... Seán M Murray
    The self-organising condensin MukBEF positions chromosomal origins in Escherichia coli..
    1. Cell Biology
    2. Computational and Systems Biology

    Decoupling global biases and local interactions between cell biological variables

    Assaf Zaritsky, Uri Obolski ... Gaudenz Danuser
    DeBias is a generic method to decompose and quantify the confounding, global factors and direct interactions of pairwise interacting variables.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis

    Gengjing Zhao, Emma S Gleave, Meindert Hugo Lamers
    Competing DNA polymerases at the DNA sliding clamp are revealed by single-molecule co-localization studies.
    1. Microbiology and Infectious Disease

    Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages

    Jonathan M Budzik, Danielle L Swaney ... Jeffery S Cox
    Measurement of post-translational modifications in primary macrophages infected with Mtb revealed phosphorylation of TAX1BP1, an autophagy receptor that enables full maturation of the Mtb autophagosome.
    1. Cell Biology
    2. Plant Biology

    Plant immune and growth receptors share common signalling components but localise to distinct plasma membrane nanodomains

    Christoph A Bücherl, Iris K Jarsch ... Cyril Zipfel
    Although genetically and biochemically linked, the plant immune and growth receptors FLS2 and BRI1 form dispersed receptor clusters within the plasma membrane that are spatiotemporally separated.
    1. Chromosomes and Gene Expression

    Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters

    Yi-Jun Sheu, Risa Karakida Kawaguchi ... Bruce Stillman
    The localization of Rad53 cell cycle checkpoint kinase to many gene promoters and the dynamic changes in response to replication stress suggests that the kinase may coordinate genome stability and gene expression.
    1. Neuroscience

    Functional independence of endogenous μ- and δ-opioid receptors co-expressed in cholinergic interneurons

    Seksiri Arttamangkul, Emily J Platt ... David Farrens
    Endogenous µ- and δ-opioid receptors do not form stable heterodimers in cholinergic interneurons.

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