6,210 results found
    1. Physics of Living Systems

    Generating active T1 transitions through mechanochemical feedback

    Rastko Sknepnek, Ilyas Djafer-Cherif ... Silke Henkes
    Directed mechanical stresses can trigger active T1 events that lead to tissue elongation perpendicular to the main direction of tissue stress.
    1. Neuroscience

    An event map of memory space in the hippocampus

    Lorena Deuker, Jacob LS Bellmund ... Christian F Doeller
    Evidence suggests a common coding mechanism underlies spatial and temporal aspects of episodic memory in the human hippocampus.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra

    Jack F Cazet, Adrienne Cho, Celina E Juliano
    Injuries activate the oral identity-specifying canonical Wnt signaling pathway in Hydra, which can trigger head regeneration in permissive tissue contexts created by the absence of pre-existing organizers.
    1. Neuroscience

    Humans parsimoniously represent auditory sequences by pruning and completing the underlying network structure

    Lucas Benjamin, Ana Fló ... Ghislaine Dehaene-Lambertz
    When exposed to sound sequences, humans compute biased transition probabilities between elements, extract the underlying network structure, and even generalize missing data.
    1. Neuroscience

    Glutamatergic supramammillary nucleus neurons respond to threatening stressors and promote active coping

    Abraham Escobedo, Salli-Ann Holloway ... Aaron J Norris
    Activation of a population of glutamatergic neurons in supramammillary nucleus enhances active coping behaviors in response to threats, offering new insights for therapeutic strategies against anxiety and mood disorders.
    1. Neuroscience

    The role of higher-order thalamus during learning and correct performance in goal-directed behavior

    Danilo La Terra, Ann-Sofie Bjerre ... Lucy M Palmer
    The higher order thalamus encodes and influences correct action during learning and performance in a sensory-based goal-directed behavior.
    1. Neuroscience

    Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca2+ channel distances

    Janus RL Kobbersmed, Andreas T Grasskamp ... Alexander M Walter
    Heterogeneous distances between vesicles and Ca2+-channels make synapses prone to short-term depression, however, Ca2+-dependent increases in the number of release-ready vesicles supports facilitation even with broadly distributed vesicle:Ca2+-channel distances.
    1. Neuroscience

    Temporo-parietal cortex involved in modeling one’s own and others’ attention

    Arvid Guterstam, Branden J Bio ... Michael Graziano
    Functional brain scans of human participants show that the brain encodes other people's attention in enough richness to distinguish whether that attention was directed exogenously (stimulus-driven) or endogenously (internally driven).
    1. Developmental Biology

    Calcium handling precedes cardiac differentiation to initiate the first heartbeat

    Richard CV Tyser, Antonio MA Miranda ... Paul R Riley
    High-resolution live imaging reveals how and when the mouse heart first starts to beat during development and how the onset of beating impacts on heart muscle cell maturation and heart formation.
    1. Computational and Systems Biology
    2. Neuroscience

    Hippocampal sharp wave-ripples and the associated sequence replay emerge from structured synaptic interactions in a network model of area CA3

    András Ecker, Bence Bagi ... Szabolcs Káli
    Simulations of a detailed network model show that the pattern of synaptic interactions resulting from learning is critical for the emergence of population bursts, sequential neuronal activity, and fast oscillations in the hippocampus.

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