Maria Ermakova, Hannah Osborn ... Susanne von Caemmerer
The SiPIP2;7 aquaporin is a functional CO2 pore that can be used to improve CO2 diffusion at the interface between the airspace and leaf mesophyll which limits C4 photosynthesis.
A novel signaling system in heart mitochondria in which the byproduct of energy metabolism, CO2/bicarbonate, acts as the primary signal to tune mitochondrial ATP production while keeping energy supply in tight synchronization with energy consumption.
Deborah H Brotherton, Sarbjit Nijjar ... Alexander David Cameron
The mutation of Lys125 in connexin26 to glutamate, a carbamylation mimetic, pushes the equilibrium of the gap junction channel seen in cryo-EM towards a more closed conformation.
Anika Küken, Frederik Sommer ... Tabea Mettler-Altmann
Mathematical models reveal that under the physiologically different conditions ambient and high CO2, two algal microcompartments are metabolically connected by facilitated transport.
Drosophila larvae foraging adapt to different food quality and distributions modulating specific motor programs, as revealed by behavioral and modeling experiments.
A series of functional assays in mouse models and primary brown adipocytes confirm that the ACE2 pathway regulates glucose and lipid homeostasis, and maintains thermogenesis and systemic energy metabolism by both the Akt and PKA signaling.
Sebastian Hückesfeld, Philipp Schlegel ... Michael J Pankratz
Core of a neuroendocrine synaptic network consists of a parallel set of interneurons that target distinct combinations of neuroendocrine outputs, thus enabling variability and flexibility in selection of physiological activity.