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A near-complete flux balance analysis model of a minimal cell demonstrates the high essentiality of its metabolic genes, agrees well with experimental essentiality data and suggests some further gene removals.

TANGO1 creates a barrier to control lipid and protein flux across fused secretory compartments.

Applying bioorthogonal chemistry to the zebrafish/Mycobacterium marinum model of tuberculosis reveals that the virulence lipid PDIM must spread into epithelial cells in order for mycobacteria to establish infection.

Dopamine release within the mouse external globus pallidus, an area of very sparse innervation, is observed and described for the first time through a new technique: flashing false fluorescent neurotransmitters.

High-quality fluorescence live-cell and single molecule imaging via computer-controlled, user-assembled microscope that fits in incubator, can in large parts be 3D printed and employs open source software and electronics.

After domestication, the cultivation range expansion of crops was not solely dictated by human activity but instead constrained by climatic factors, which in turn resulted in distinct phenotypic characteristics of locally adaptive landraces.

A GABAergic neural circuit from AgRP to the dorsomedial hypothalamic nucleus regulates leptin-mediated feeding and energy balance through α3-GABAA signaling, which could provide a new therapeutic avenue for obesity.

The introduced Python tool was used to characterize breathing behaviors of common marmosets in room air and acute hypoxic (10% O₂) and hypercapnic (6% CO₂) conditions.