Acetylcholine, a common modulator in the brain, controls spike-frequency adaptation by specifically attenuating Ether-a-go-go related K+ currents, thereby explaining many cortical network statistical changes often observed in vivo.
Psychophysics experiments and EEG recordings reveal that people's performance in detecting unexpected changes in complex auditory scenes can be modeled as a process of sensory evidence accumulation.
Novel brainstem organotypic cultures that generate rhythmic respiratory motor activity reveal the neural networks that control breathing and a new pathway in the hypercapnic response.
While intact mir-17-92 acts as a potent oncogene in a mouse model of Burkitt’s lymphoma, one of the six mir-17-92 components antagonizes its oncogenic cooperation with c-Myc by promoting c-Myc-induced apoptosis.
ENU mutagenesis in pigs is an efficient strategy to introduce mutations at the whole-genome level and mutants have been generated on a large scale for agricultural production and biomedical research.
Intracellular recordings in singing birds and images of synapses in deafened birds provide insights into the neural circuitry that enables songbirds to fine-tune their songs.
The aged human auditory cortex shows preserved tonotopy, but temporal modulations are represented with a markedly broader tuning, highlighting decreased temporal selectivity as a hallmark of the aging auditory cortex.