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    1. Neuroscience

    The organizational principles of de-differentiated topographic maps in somatosensory cortex

    Peng Liu, Anastasia Chrysidou ... Esther Kuehn
    SI topographic finger maps of older adults show signs of cortical aging but do not show classical hallmarks of cortical de-differentiation.
    1. Cell Biology
    2. Neuroscience

    Pregnancy-associated plasma protein-aa regulates endoplasmic reticulum–mitochondria associations

    Mroj Alassaf, Mary C Halloran
    An extracellular modulator of IGF1 signaling, Pappaa, regulates endoplasmic reticulum–mitochondria connections, which are critical for metabolic homeostasis and hair cell survival.
    1. Cancer Biology

    The identification of dual protective agents against cisplatin-induced oto- and nephrotoxicity using the zebrafish model

    Jaime N Wertman, Nicole Melong ... Jason N Berman
    L-mimosine and dopamine protect against cisplatin-induced oto- and nephrotoxicity in zebrafish and human cell line models.
    1. Developmental Biology
    2. Neuroscience

    Synaptic mitochondria regulate hair-cell synapse size and function

    Hiu-tung C Wong, Qiuxiang Zhang ... Katie Kindt
    Mitochondrial calcium influx plays distinct roles in presynapse formation, function and stability in sensory hair cells.
    1. Cell Biology
    2. Neuroscience

    Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells

    Sarah B Pickett, Eric D Thomas ... David W Raible
    The history of mitochondrial activity predicts whether zebrafish mechanosensory hair cells live or die after toxic drug exposure.
    1. Chromosomes and Gene Expression

    Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss

    Meritxell Espino Guarch, Mariona Font-Llitjós ... Virginia Nunes
    SLC7A8 a neutral amino acid transporter has a key role in the maintenance of hearing during aging and its absence causes early onset of hearing loss.
    1. Neuroscience

    Subcellular analysis of pigeon hair cells implicates vesicular trafficking in cuticulosome formation and maintenance

    Simon Nimpf, Erich Pascal Malkemper ... David A Keays
    Cuticulosomes are organelles found in the hair cells of birds that are composed of ferritin nanoparticles, form rapidly after hatching by the fusion of vesicular structures, and may play an indirect role in magnetic sensation.
    1. Developmental Biology

    Pilot study of large-scale production of mutant pigs by ENU mutagenesis

    Tang Hai, Chunwei Cao ... Anming Meng
    ENU mutagenesis in pigs is an efficient strategy to introduce mutations at the whole-genome level and mutants have been generated on a large scale for agricultural production and biomedical research.
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