126 results found
    1. Neuroscience

    Identification of an inhibitory neuron subtype, the L-stellate cell of the cochlear nucleus

    Tenzin Ngodup et al.
    A major new class of neuronal cell type has been discovered in the auditory system, having features that make it a critical component of auditory processing.
    1. Neuroscience

    Inhibition in the auditory brainstem enhances signal representation and regulates gain in complex acoustic environments

    Christian Keine et al.
    Inhibition in the brainstem has further roles beyond temporal sharpening and improves reproduction for a multitude of sounds.
    1. Neuroscience

    A novel class of inferior colliculus principal neurons labeled in vasoactive intestinal peptide-Cre mice

    David Goyer et al.
    VIP neurons are a novel class of inferior colliculus stellate neurons that project to long-range auditory and non-auditory targets and integrate inputs from the auditory brainstem and contralateral IC.
    1. Neuroscience

    Distinct forms of synaptic plasticity during ascending vs descending control of medial olivocochlear efferent neurons

    Gabriel E Romero, Laurence O Trussell
    In a fast brainstem relay controlling hearing sensitivity, descending synaptic control from midbrain provides the dominant source of excitation, due to a distinct form of synaptic plasticity.
    1. Neuroscience

    Signal integration at spherical bushy cells enhances representation of temporal structure but limits its range

    Christian Keine et al.
    Inhibition reduces the neuronal representation of acoustic signals to enhance temporal precision in the auditory brainstem.
    1. Neuroscience

    Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus

    Shuang Li et al.
    Mice that successfully avoid developing tinnitus despite exposure to excessive noise show spontaneous recovery of KCNQ2/3 potassium channel activity associated with a reduction in HCN channel activity in auditory brainstem neurons.
    1. Developmental Biology
    2. Neuroscience

    Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space

    Travis A Babola et al.
    Supporting cells in the cochlea change their shape in response to purinergic receptor activation, which influences hair cell excitability by altering potassium redistribution in the extracellular space.
    1. Developmental Biology

    Retrograde ERK activation waves drive base-to-apex multicellular flow in murine cochlear duct morphogenesis

    Mamoru Ishii et al.
    Live-cell imaging and mathematical modeling reveal the physical basis of collective cell migration underlying spiral cochlear duct formation during murine inner ear development.
    1. Neuroscience

    Mapping the human subcortical auditory system using histology, postmortem MRI and in vivo MRI at 7T

    Kevin R Sitek et al.
    MRI methods are promising techniques for investigating the human subcortical auditory system, and these publicly available data, atlases, and tools make researching human audition simpler and more reliable.
    1. Neuroscience

    Vocalization–whisking coordination and multisensory integration of social signals in rat auditory cortex

    Rajnish P Rao et al.
    Snout-to-snout contact modulates the response of rat auditory cortex to calls from other animals, indicating that the multisensory nature of social interaction is directly represented in the rat brain.

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