894 results found
    1. Neuroscience

    Stimulating the hippocampal posterior-medial network enhances task-dependent connectivity and memory

    Kristen N Warren et al.
    Noninvasive stimulation of hippocampal networks increases connectivity in a functionally-specific manner that is highly relevant to effective episodic memory performance that depends on the targeted network.
    1. Developmental Biology
    2. Neuroscience

    Shifts in myeloarchitecture characterise adolescent development of cortical gradients

    Casey Paquola et al.
    Layer-specific microstructural changes contribute to the maturation of cortical organisation during adolescence.
    1. Neuroscience

    Behavior: The cerebellum shows its stripes

    Ashley L Holloway, Talia N Lerner
    New studies examine how the different sub-structures in the cerebellum are organized to receive information during complex behavioral tasks.
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    1. Neuroscience

    Structured inhibitory activity dynamics in new virtual environments

    Moises Arriaga, Edward B Han
    Inhibitory interneuron activity is dynamically modulated in new environments while individual interneurons show consistent levels of activity modulation across multiple environments, suggesting functional specialization of inhibitory subnetworks.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure-based inhibitors of amyloid beta core suggest a common interface with tau

    Sarah L Griner et al.
    Aβ inhibitors effectively block its aggregation, while also reducing seeding of tau aggregation from Aβ, tau, and AD derived fibrils, suggesting the two share a structurally related disease relevant interface.
    1. Neuroscience

    The effects of psychosocial stress on dopaminergic function and the acute stress response

    Michael AP Bloomfield et al.
    Imaging and laboratory-induced psychosocial stress showed that exposure to psychosocial adversity was associated with dampened striatal dopaminergic function alongside blunted physiological yet potentiated subjective responses to acute stress.
    1. Evolutionary Biology

    The Natural History of Model Organisms: Insights into the evolution of social systems and species from baboon studies

    Julia Fischer et al.
    Wild baboons are an excellent model to study complex evolutionary processes such as speciation and hybridization, as well as the links between sociality, longevity and reproductive success.
    1. Neuroscience

    Brain Development: The impact of light during the night

    Sophia TC Leung et al.
    Exposing chicks to one hour of light during the night disrupts the releaseof a hormone that is needed by cells in the developing brain to survive.
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    1. Neuroscience

    Modular organization of cerebellar climbing fiber inputs during goal-directed behavior

    Shinichiro Tsutsumi et al.
    Motor and non-motor functions are represented in spatially segregated and temporally organized climbing fiber signals to distinct cerebellar zones during goal-directed behavior.
    1. Neuroscience

    Classical conditioning drives learned reward prediction signals in climbing fibers across the lateral cerebellum

    William Heffley, Court Hull
    Cerebellar climbing fibers can generate learned reward-predictive instructional signals, suggesting a role for cerebellar learning in the reinforcement of reward-driven behaviors.

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