6,097 results found
    1. Developmental Biology

    In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer

    Li He et al.
    A simple and effective method facilitates the study of in vivo transcriptional dynamics using transcriptional enhancers and destabilized fluorescent protein, which is suitable for both live imaging and fixed studies.
    1. Cancer Biology

    A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis

    Ming Chao et al.
    Local infusion of bicarbonate into hepatocellular carcinoma markedly enhances local tumor control by transarterial chemoembolization.
    1. Epidemiology and Global Health

    Body height in young adult men and risk of dementia later in adult life

    Terese Sara Høj Jørgensen et al.
    Taller body height in young adulthood, as marker of early-life environment, is associated with lower risk of dementia diagnosis independently of cognitive reserve and family factors shared among brothers.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Transmission dynamics and control of multidrug-resistant Klebsiella pneumoniae in neonates in a developing country

    Thomas Crellen et al.
    Colonisation with resistant Klebsiella pneumoniae in a Cambodian neonatal unit is driven by person-to-person transmission, transmissibility varies by sequence type, and antibiotic consumption generally increases the risk of acquisition.
    1. Epidemiology and Global Health

    Childhood injury after a parental cancer diagnosis

    Ruoqing Chen et al.
    Children with a parent of cancer have a higher rate of hospital contact for injury, especially immediately after the cancer diagnosis.
    1. Human Biology and Medicine
    2. Neuroscience

    Family history of Alzheimer’s disease alters cognition and is modified by medical and genetic factors

    Joshua S Talboom et al.
    An internet-based cohort study of paired associate learning shows that a first-degree family history of dementia is associated with lowered performance, an effect modified by apolipoprotein E genotype and diabetes.
    1. Epidemiology and Global Health

    Autism and attention-deficit/hyperactivity disorder among individuals with a family history of alcohol use disorders

    Jan Sundquist et al.
    A Swedish national cohort study reveals that children with a family history of alcohol use disorders have an increased risk of autism and attention-deficit/hyperactivity disorder.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor

    Anastasiia Stratiievska et al.
    A dual-color TIRFM study reveals a new form of inflammatory regulation, in which a lipid kinase and ion channel reciprocally regulate each other to amplify the response to painful stimuli.
    1. Microbiology and Infectious Disease

    Regulation of life span by the gut microbiota in the short-lived African turquoise killifish

    Patrick Smith et al.
    Resetting a young gut microbiota in middle-aged individuals extends life span and slows aging in the naturally short-lived turquoise killifish, a new vertebrate model organism to study how the microbiota affects the aging process.

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