Depletion of VAPA in cancer cells induces defects in actin organization, adhesion dynamics and cell migration, together with a perturbation of phosphoinositide levels at the plasma membrane and a lack of anchoring of ER-PM contact sites to focal adhesions.

A close approximation to the successor representation is learnt by a simple spike-time-dependent learning rule between cells undergoing theta phase precession.

Transport-based high-throughput identification of cargo proteins specific to all 12 human importin-β family nuclear import receptors revealed biological processes that the cargo cohorts of each receptor are involved in.

Epithelial tissue remodeling during Drosophila embryonic development is quantitatively described by a simple law relating myosin activity and cell flow.

Radial alignment in confined cell monolayers with isotropic actin network is found to be mediated by the condensation tendency and tissue-scale actin gradient.

Mathematical modeling shows that reproductive specialization is strongly favored in sparse networks of cellular interactions that reflect the morphology of early multicellular organisms, even when benefits of specialization are saturating.

Using self-organization, cells can collectively leverage defects in nematic and hexatic orders to localize mechanical stresses and remove an unwanted cell with their preferred path to achieve this explored here by independently tuning cell–cell and cell–substrate adhesion strengths.

NR4A is a broadly conserved transcription factor that is required for concordance of patterning information and anatomy at both ends of the planarian anterior-posterior axis.

A common genomic deletion in various human cancers disrupts mitochondrial protein homeostasis in a way that might be targeted by existing drugs.