A protein called PVRL4 has a central role in a number of cancers that originate in epithelial tissue, and anti-PVRL4 antibodies could be used to treat some of these cancers.

Science is an essential component of policy-making in most areas of government, but the scientific community does not always understand its role in this process.

Two cooperative populations of yeast cells that cannot distinguish between cooperative partners and cheating intruders can still self-organize into clusters that exclude cheaters.

The transition to the aggregative stage of Capsaspora owczarzaki, a close unicellular relative to Metazoa, is associated with significant upregulation of orthologs of genes that are important for multicellularity in metazoans.

Comparative electron tomography of growing flagellar tips reveals that axonemal growth differs between short and long flagella, and between species.

One-quarter of the Chondrichthyes have an elevated risk of extinction, mainly as a result of overfishing.

Analysis of multiple guanine exchange factors shows that Rab activation can occur via a number of mechanistically distinct GDP-release pathways.

A starvation-induced drop in cytosolic pH promotes assembly of budding yeast glutamine synthetase into enzymatically inactive filaments that function as enzyme storage depots.

Increasing levels of atmospheric carbon dioxide reduce the mineral content but increase the levels of starch and sugars found in crop plants; which could exacerbate both obesity and malnutrition in some human populations.

The soluble cargo protein albumin traverses the Golgi stack at much faster rates than procollagen aggregates, by diffusion via intercisternal continuities.