4,924 results found
    1. Neuroscience

    An excitatory cortical feedback loop gates retinal wave transmission in rodent thalamus

    Yasunobu Murata, Matthew T Colonnese
    The absence of functional inhibition is a developmentally transient circuit property of corticothalamic feedback that is essential for the central transmission of spontaneous retinal waves.
    1. Neuroscience

    Synaptic and circuit mechanisms prevent detrimentally precise correlation in the developing mammalian visual system

    Ruben A Tikidji-Hamburyan, Gubbi Govindaiah ... Matthew T Colonnese
    The imprecise and broad connectivity of retinal inputs during development have the potential to generate large correlations in target neurons that reduce retinotopic information unless suppressed by the special synaptic and circuit properties present at these ages.
    1. Computational and Systems Biology
    2. Ecology

    Nomadic-colonial life strategies enable paradoxical survival and growth despite habitat destruction

    Zhi Xuan Tan, Kang Hao Cheong
    By modelling organisms that alternate between individual and colonial lifestyles, the well-known Parrondo's paradox can emerge in an ecological setting without the need for stochastic environmental variation.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Spatial alanine metabolism determines local growth dynamics of Escherichia coli colonies

    Francisco Díaz-Pascual, Martin Lempp ... Knut Drescher
    An investigation of spatiotemporal metabolic differentiation during colony biofilm growth of E. coli revealed that alanine is cross-fed between spatially segregated subpopulations within the colony, to support cellular growth in an otherwise nutrient-deprived region of the colony.
    1. Ecology

    Ant colonies maintain social homeostasis in the face of decreased density

    Andreas P Modlmeier, Ewan Colman ... David P Hughes
    Organizational resilience allows ant colonies to retain high interaction rates in the face of decreased density by altering their spatial and social dynamics.
    1. Developmental Biology
    2. Genetics and Genomics

    The genome sequence of the colonial chordate, Botryllus schlosseri

    Ayelet Voskoboynik, Norma F Neff ... Stephen R Quake
    The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.
    1. Evolutionary Biology

    An adjunctive therapy administered with an antibiotic prevents enrichment of antibiotic-resistant clones of a colonizing opportunistic pathogen

    Valerie J Morley, Clare L Kinnear ... Andrew F Read
    Cholestyramine, an FDA-approved bile acid sequestrant, can be repurposed to inactivate the antibiotic daptomycin in the gut, which prevents the emergence of transmissible antibiotic resistance in gastrointestinal Enterococcus faecium populations.
    1. Ecology
    2. Evolutionary Biology

    Sex-specific effects of cooperative breeding and colonial nesting on prosociality in corvids

    Lisa Horn, Thomas Bugnyar ... Jorg JM Massen
    A systematic experimental comparison of prosocial behavior in eight corvid species reveals sex-specific effects of cooperative breeding and colonial nesting, thereby adding important new insights regarding the evolution of prosociality.
    1. Microbiology and Infectious Disease

    Multi-omics investigation of Clostridioides difficile-colonized patients reveals pathogen and commensal correlates of C. difficile pathogenesis

    Skye RS Fishbein, John I Robinson ... Gautam Dantas
    Integration of clinical patient data, pathogen information and a multi-omic analysis of the gut microbiome reveals key determinants of disease in C. difficile-colonized patients.
    1. Immunology and Inflammation

    Compartmentalization and persistence of dominant (regulatory) T cell clones indicates antigen skewing in juvenile idiopathic arthritis

    Gerdien Mijnheer, Nila Hendrika Servaas ... Femke van Wijk
    In localized autoimmune disease, there is autoantigen-driven expansion of both effector T cell and Treg clones that are highly persistent and are (re)circulating, and might represent interesting therapeutic targets.

Refine your results by:

Type
Research categories