3,260 results found
    1. Cancer Biology
    2. Stem Cells and Regenerative Medicine

    A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division

    Lihua Wang et al.
    A novel long non-coding RNA targets microRNA miR-34a for epigenetic silencing and initiates asymmetric division of colon cancer stem cells.
    1. Evolutionary Biology
    2. Neuroscience

    True S-cones are concentrated in the ventral mouse retina and wired for color detection in the upper visual field

    Francisco M Nadal-Nicolás et al.
    Unique 'true' S-cone and S-cone bipolar cell distribution patterns in the mouse retina are previously unappreciated anatomical features that support enhanced short-wavelength signaling for color detection above horizon.
    1. Evolutionary Biology

    Multifactorial processes underlie parallel opsin loss in neotropical bats

    Alexa Sadier et al.
    Parallel losses of short-wave light sensitivity in diverse bats occurred through independent changes at multiple steps in the conversion of genotype into functional phenotype, including pre-, during, and post-transcription.
    1. Neuroscience

    A quadratic model captures the human V1 response to variations in chromatic direction and contrast

    Michael A Barnett et al.
    A quantitative forward model captures fMRI responses to chromatic stimuli in human primary visual cortex and quantifies how chromatic sensitivity changes with eccentricity.
    1. Neuroscience

    Visual mode switching learned through repeated adaptation to color

    Yanjun Li et al.
    The visual system can learn to rapidly adjust itself through experience, switching modes to stabilize vision perception and optimize perceptual processes.
    1. Neuroscience

    Mouse color and wavelength-specific luminance contrast sensitivity are non-uniform across visual space

    Daniel J Denman et al.
    Mice can detect changes in hue independent of luminance, with differing sensitivity to hue and luminance in different parts of visual space.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Complementary shifts in photoreceptor spectral tuning unlock the full adaptive potential of ultraviolet vision in birds

    Matthew B Toomey et al.
    Birds that see ultraviolet light tune the sensitivity of their short-wavelength photoreceptors with colored filters to maximize the number of colors they can see.
    1. Computational and Systems Biology
    2. Neuroscience

    On the dimensionality of odor space

    Markus Meister
    A recent claim that humans can discriminate 1 trillion odors is found to be unwarranted, and further analysis offers insights into the dimensionality of olfactory perception.
    1. Neuroscience

    anTraX, a software package for high-throughput video tracking of color-tagged insects

    Asaf Gal et al.
    anTraX is an algorithm and software package that facilitates automated analyses of insect social behavior in species and experimental settings that are not accessible with currently existing technology.
    1. Structural Biology and Molecular Biophysics

    Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis

    Trayambak Pathak et al.
    Colorectal tumors down-regulate the mitochondrial Na+/Ca2+/Li+ exchanger (NCLX) to alter mitochondrial Ca2+ signaling and initiate transcriptional and metabolic reprogramming that drives tumor chemo-resistance and metastasis.

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