Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.
Kathryn H Fife, Navarre A Gutierrez-Reed ... Thomas S Hnasko
Activation of the subthalamic nucleus (STN) pauses or disrupts behavior, while STN inhibition reduces the disruptive effects of surprise, indicating that STN activation is both sufficient and necessary for behavioral inhibition.
Dopamine neurons make novel glutamatergic connections to striatal cholinergic interneurons in the lateral dorsal striatum that are mediated by metabotropic glutamate receptors coupled to TrpC channels.
Anne Löffler, Ariel Zylberberg ... Daniel M Wolpert
Deciding which of two perceptual decisions is more difficult involves sequential sampling processes that terminate when the difference in accumulated evidence for each decision exceeds a threshold.
As a Russian doll, mimivirus dsDNA genome is folded in a nucleocapsid-like structure enclosed in the nucleoid compartment, encased in the icosahedral capsid itself decorated by long glycosylated fibrils surprisingly made of the same protein as the genomic fiber.
Alex W Chan, Malgorzata Broncel ... Sebastian Lourido
Comprehensive characterization of kinase-dependent phosphorylation in the human pathogen Toxoplasma gondii identifies a trafficking adaptor complex required for virulence factor secretion and infection.
