370 results found
  1. October 2013

    Episode 5: October 2013

    In this episode we hear about how chimpanzees use conceptual metaphors, hyperactive sperm, the use of bacteria to estimate the time of death, stem cells and smoking, and a new type of bacteria.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease
    Tropical disease

    Tropical Disease: A Collection of Articles

    Edited by Prabhat Jha et al.
    eLife has published papers on many tropical diseases, including malaria, Ebola, leishmaniases, Dengue and African sleeping sickness.
  2. Episode 45: February 2018

    In this episode, we hear about disease control in insects, placental development, post-traumatic stress disorder, the mission to create a human cell atlas and how crickets amplify their song.
    1. Cell Biology
    2. Developmental Biology

    Proliferation-independent regulation of organ size by Fgf/Notch signaling

    Agnė Kozlovskaja-Gumbrienė et al.
    Cell adhesion regulates organ size in the zebrafish lateral line system.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Further support for aneuploidy tolerance in wild yeast and effects of dosage compensation on gene copy-number evolution

    Audrey P Gasch et al.
    Many natural isolates of budding yeast carry extra chromosome copies and show lower-than-expected expression at a subset of amplified genes, which show unique evolutionary signatures.
    1. Computational and Systems Biology

    RNA polymerase errors cause splicing defects and can be regulated by differential expression of RNA polymerase subunits

    Lucas B Carey
    A single human cell makes 10-100 transcriptional errors per second; these errors affect splicing and may influence the evolution of coding sequences.
    1. Ecology

    Extinction risk and conservation of the world’s sharks and rays

    Nicholas K Dulvy et al.
    One-quarter of the Chondrichthyes have an elevated risk of extinction, mainly as a result of overfishing.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA

    Flora S Groothuizen et al.
    Visualization of the sliding clamp in DNA mismatch repair shows how a transient complex is activated.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline

    Mayu Inaba et al.
    The stem cell orientation checkpoint senses the correct orientation of centrosomes via their interactions with a protein called Bazooka.
    1. Developmental Biology
    2. Genetics and Genomics

    Zygotic gene activation in the chicken occurs in two waves, the first involving only maternally derived genes

    Young Sun Hwang et al.
    In Aves, the first wave of transcription is derived exclusively from the maternal genome.

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