1,111 results found
    1. Neuroscience

    Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

    Eric Kenji Lee, Hymavathy Balasubramanian ... Chandramouli Chandrasekaran
    WaveMAP is a novel approach that combines nonlinear dimensionality reduction with graph clustering on extracellular waveforms to reveal previously obscured cell type diversity in monkey cortex.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Differential regulation by CD47 and thrombospondin-1 of extramedullary erythropoiesis in mouse spleen

    Rajdeep Banerjee, Thomas J Meyer ... David D Roberts
    Increased extramedullary erythropoiesis in spleen compensates for the elevated turnover of red blood cells in mice lacking CD47, but extramedullary erythropoiesis is suppressed in mice lacking the CD47 ligand thrombospondin-1.
    1. Neuroscience

    Sub-second dynamics of theta-gamma coupling in hippocampal CA1

    Lu Zhang, John Lee ... Annabelle C Singer
    A combination of signal processing and machine learning form a new approach to classify oscillatory coupling in single cycles without averaging over time and to capture cycle-by-cycle changes in coupling.
    1. Computational and Systems Biology

    Comprehensive and unbiased multiparameter high-throughput screening by compaRe finds effective and subtle drug responses in AML models

    Morteza Chalabi Hajkarim, Ella Karjalainen ... Kyoung-Jae Won
    compaRe can be used to optimize cytometric high-parameter immunophenotypic characterization of heterogeneous cell populations.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Household clustering and seasonal genetic variation of Plasmodium falciparum at the community-level in The Gambia

    Marc-Antoine Guery, Sukai Ceesay ... Antoine Claessens
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Common cell type nomenclature for the mammalian brain

    Jeremy A Miller, Nathan W Gouwens ... Amy Bernard
    A new nomenclature convention for mammalian cell types utilizing shared taxonomies and quantitative cell features is applied to high-quality, open data from the mouse and human brain.
    1. Ecology
    2. Genetics and Genomics

    Genomic evidence for global ocean plankton biogeography shaped by large-scale current systems

    Daniel J Richter, Romain Watteaux ... Olivier Jaillon
    Analysis of genomic DNA composition of surface plankton communities reveals a stable, ocean basin-scale plankton biogeography that emerges from the intertwined effects of environmental variations and currents.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Potential herd protection against Plasmodium falciparum infections conferred by mass antimalarial drug administrations

    Daniel M Parker, Sai Thein Than Tun ... François Nosten
    Given sufficient population adherence, mass drug administration for falciparum malaria can provide group level benefits, also known as ‘herd effects’.
    1. Neuroscience

    Functional connectivity subtypes associate robustly with ASD diagnosis

    Sebastian GW Urchs, Angela Tam ... Pierre Bellec
    Unsupervised clustering of the heterogeneous functional brain organization in autism reveals generalizable patterns of connectivity alterations that extend to the general population.
    1. Ecology

    Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly

    Inés Martínez, Maria X Maldonado-Gomez ... Jens Walter
    Experiments in ex-germ-free mice establish a measurable effect of colonization history on gut microbiota assembly, illuminating a potential cause for the high levels of unexplained individuality in host-associated microbial communities.

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