A high-throughput method to profile tyrosine kinases and phosphotyrosine recognition domains reveals new rules for sequence specificity and maps the effects of mutations on the recognition of tyrosine phosphorylation sites.

The human brain encodes coordinated patterns of joint movements – synergies – to increase the efficiency with which it can control complex hand movements.

Ketamine, an NMDA receptor antagonist and experimental model for schizophrenia, produces decision-making deficits in monkeys, which are predicted by a lowering of cortical excitation-inhibition balance in a spiking circuit model.

While Trypanosoma congolense is mostly known to cause a chronic wasting disease in animals, a new mouse model shows that acute cerebral trypanosomiasis is triggered by parasite sequestration and infiltration of T helper cells in the brain parenchyma.

Fluctuations of spectral power in large-scale cortical networks shape behavior in a perceptual decision-making task through arousal-linked and arousal-independent mechanisms.

Learning in children with autism spectrum disorder (ASD) was achieved by fundamentally different cognitive and neural mechanisms from typically developing children, and insistence on sameness, a core symptom of ASD, contributed to such atypical mechanisms of learning in affected children.

A phase shift between local contractions drives 3D cell motility in experiments and in model or how a finite area in the dipole-quadrupole space explains cell motion with zero total force.

Among the factors that predict fitness in wild baboons, dominance rank in males, but not in females, is the best predictor of epigenetic aging.

A combination of single-cell RNA sequencing of the developing septum and genetic fate mapping is used to analyze the origin of septal neurons.

A new method for analyzing continuous psychophysics experiments estimates not only perceptual uncertainty from tracking tasks but also action variability, intrinsic costs, and subjective internal models.