1,747 results found
    1. Neuroscience

    Conserved neural circuit structure across Drosophila larval development revealed by comparative connectomics

    Stephan Gerhard et al.
    The connectivity structure of a nociceptive circuit is precisely maintained over Drosophila larval development through cell type-specific increases in synaptic contacts as measured from electron microscopy reconstructions, while individual neurons grow five-fold in size and number of synapses.
    1. Developmental Biology

    Developmental evolution of the forebrain in cavefish, from natural variations in neuropeptides to behavior

    Alexandre Alié et al.
    A comparative approach shows that developmental evolution of neuropeptidergic neuronal groups in the hypothalamus of blind cavefish drives adaptive behavioral evolution.
    1. Developmental Biology

    Spatial patterning of liver progenitor cell differentiation mediated by cellular contractility and Notch signaling

    Kerim B Kaylan et al.
    Mechanical stress plays a cooperative role with Notch in biliary differentiation of liver progenitors, supporting a model of liver development in which biomechanical cues are key inducers of cell fate.
    1. Plant Biology

    The role of APETALA1 in petal number robustness

    Marie Monniaux et al.
    Variable petal number in Cardamine hirsuta is explained by regulatory changes in the MADS-box gene APETALA1 that relaxed its epistasis over mapped QTL in the C. hirsuta genome.
    1. Neuroscience

    Locomotion: Building behaviors, one layer at a time

    Claire Wyart, Vatsala Thirumalai
    New interneurons are added in the hindbrain to support more complex movements as young zebrafish get older.
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  1. Point of view: Motivating participation in open science by examining researcher incentives

    Sarah E Ali-Khan et al.
    A survey of researchers at the Montreal Neurological Institute and Hospital provides insights into the challenges and opportunities involved in adopting an open science policy across an entire patient-oriented academic institution.
    1. Developmental Biology
    2. Neuroscience
    Pond snail illustration

    The Natural History of Model Organisms: The unlimited potential of the great pond snail, Lymnaea stagnalis

    István Fodor et al.
    The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.
    1. Computational and Systems Biology

    Meta-Research: Centralized scientific communities are less likely to generate replicable results

    Valentin Danchev et al.
    Analysis of data on drug-gene interactions suggests that decentralized collaboration will increase the robustness of scientific findings in biomedical research.
    1. Developmental Biology
    Ciona intestinalis illustration

    The Natural History of Model Organisms: An organismal perspective on C. intestinalis development, origins and diversification

    Matthew J Kourakis, William C Smith
    The life cycle and morphology of the sea squirt Ciona intestinalis shed light on vertebrate evolution.

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