Browse the search results

Page 2 of 349
  1. Episode 50: October 2018

    In this special episode, we discuss how tiny microbes in the gut – the microbiome – can have a huge impact on the lives of animals.
  2. Episode 47: May 2018

    In this episode, we hear about echolocation in bats, open science, a new use for aspirin, brain topography, and combining science and parenthood.
    1. Neuroscience

    Confidence predicts speed-accuracy tradeoff for subsequent decisions

    Kobe Desender et al.
    Neural coding of previous-trial confidence affects current decision policy.
    1. Microbiology and Infectious Disease

    A single regulator NrtR controls bacterial NAD+ homeostasis via its acetylation

    Rongsui Gao et al.
    Functional definition of NrtR and the discovery of its acetylation represents a first paradigm for linking protein acetylation to bacterial central NAD+ metabolism.
    1. Developmental Biology
    2. Evolutionary Biology

    Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment

    Kate A Rawlinson et al.
    A new opsin receptor is light-sensitive and expressed in a unique type of photoreceptor in a flatworm that encloses over 400 sensory cilia within its cell membrane.
    1. Immunology and Inflammation

    Circulating T cell-monocyte complexes are markers of immune perturbations

    Julie G Burel et al.
    Human blood contains T cell-monocyte complexes which are not technical artefacts but reflect true in vivo immune cell interactions.
    1. Ecology
    2. Evolutionary Biology

    Signal categorization by foraging animals depends on ecological diversity

    David William Kikuchi et al.
    In richer, more even communities, foragers form broad categories among their food resources that can select for convergence among signals, including mimetic resemblances.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity

    Wenlei Ye et al.
    TMEM16F shifts its ion selectivity in response to change of intracellular Ca2+, membrane potential and ionic strength.
    1. Immunology and Inflammation

    Synergy and remarkable specificity of antimicrobial peptides in vivo using a systematic knockout approach

    Mark Austin Hanson et al.
    While antimicrobial cocktails are highly effective for defence against pathogenic microbes, the innate immune response may instead employ highly specific peptidic antibiotics to combat certain natural enemies.
    1. Cancer Biology
    2. Cell Biology

    Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2

    Qian Liu et al.
    The pro-apoptotic BH3-protein Bim contains two distinct binding sites for anti-apoptotic proteins that together confer resistance of Bim/Bcl-2 and Bim/Bcl-XL complexes to BH3-mimetic drugs under development for use in humans.