The therapeutic effects of the sleeping pill zolpidem in patients with disorders of consciousness may be due to recruitment of brain cells idling in abnormally low-frequency brain waves.

A mathematical model built around the assumption that the desire to maintain internal homeostasis drives the behavior of animals, by affecting their learning processes, can explain many real-world behaviors, including some that might otherwise appear irrational.

During quiet wakefulness but not slow wave sleep, reward modulated VTA neurons coordinate selectively with hippocampal replay sequences and are biased in their timing towards the reactivated representation of reward locations.

Protein kinase A regulates the rapid, activity-dependent genesis of excitatory synapses during striatal development.

Within the monkey orbitofrontal cortex, a posterior part learns new values, whereas an anterior part translates this knowledge into advantageous decisions.

An evolutionarily conserved mechanism involving translational control by p-eIF2α underlies vulnerability to nicotine addiction.

A dimensional approach to psychiatry demonstrates the specificity and generalizability of a neurocognitive marker of compulsive behavior and intrusive thought via large-scale online testing.

Epigenetic reprogramming by LSD1/KDM1A acts at fertilization in mice to enable embryogenesis and prevent behavioural abnormalities.