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Viral evolution can lead to mutations that render specific glycosylation sites dispensable for folding and for supporting the protein's function, allowing changes in the shield, and in the immunogenic profile.

Both protein-protein and protein-lipid interactions are essential for Rab5 symmetry breaking at the early endosome.

Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?

The odor-elicited responses of olfactory receptor neurons consist of a discrete set of four spike pattern motifs, each with distinct adaptation properties, together amplifying distinctions between similar and temporally complex chemical inputs such as odor plumes.

Structure modeling, site-directed mutagenesis, and current recordings revealed the mechanism by which stabilization of voltage sensors in the resting and activated states determines the gating properties of the Ca_V1.1 calcium channel.

By centralizing many of the tasks associated with the upkeep of scientific software, SBGrid allows researchers to spend more of their time on research.

In feedforward networks with random connectivity, connection motifs underlying the detection of short clusters and activity sequences are likely to converge on a subset of postsynaptic neurons purely by chance.

Wikidata is continuously-updated resource that could improve the efficiency and accuracy of research in many areas of the life and biomedical sciences.

An individual-based model framework of sub-exponentially growing replicator systems suggests that parabolic dynamics could have been able to maintain genetic diversity and circumvent the error threshold problem during early evolution.