Stem cell self-renewal strategies fall into two classes, and only strategies of different classes can be experimentally distinguished via static clonal data.

A new method to infer the spatial history of genetic ancestors from a sequence of trees along a recombining genome.

Geometrical features of microtubule arrays regulate the collective activity of motor and non-motor proteins.

Selection for asymmetric signalling between gametes explains the very origins of sexual asymmetry as seen in mating-types with morphologically similar but self-incompatible gametes.

An experimentally constrained multiscale mathematical model predicts that branched actin networks self-organize at endocytic sites and bend to produce force, which was verified with cryo-electron tomography of intact cells.

The synaptic ribbon regulates calcium channel clustering and proper vesicle dynamics at cochlear inner hair cells to ensure precise sound encoding.

Electrophysiology and optogenetic circuit manipulation in the mouse visual system reveal that corticothalamic feedback and behavioral state both have robust modulatory, yet largely independent influences on thalamic responses to naturalistic movies.

The combination of short-term and long-term plasticity enables hippocampus to learn goal-directed paths through replay in a reversed order.

External hydrodynamic forcing on each flagellum of Chlamydomonas reinhardtii reveals a leader-follower relation between the two flagella in the synchronous beating.

A combination of genetic and biochemical approaches suggest that yeast Rev7 promotes DNA double-strand break repair via NHEJ and inhibits homologous recombination by blocking Mre11 nuclease and Rad50’s ATPase activities.