2,185 results found
    1. Cell Biology

    Multi-phosphorylation reaction and clustering tune Pom1 gradient mid-cell levels according to cell size

    Veneta Gerganova et al.
    Advanced microscopy techniques reveal that clusters of Pom1 kinase at the membrane represent the functional unit that shape the concentration gradients and modulate Pom1 mid-cell levels according to cell size.
    1. Cell Biology

    Stable Pom1 clusters form a glucose-modulated concentration gradient that regulates mitotic entry

    Corey A H Allard et al.
    Dynamic signaling protein clusters sample and map the cell surface to ensure that cells divide at the proper size.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Concentration dependent chromatin states induced by the bicoid morphogen gradient

    Colleen E Hannon et al.
    Interplay between protein concentration, DNA binding and remodeling of the chromatin landscape in early embryogenesis determines how a single transcription factor can specify multiple distinct gene expression states.
    1. Physics of Living Systems

    Sperm chemotaxis is driven by the slope of the chemoattractant concentration field

    Héctor Vicente Ramírez-Gómez et al.
    The slope of the chemoattractant concentration gradient is a driving force for sperm chemotaxis, by coordinating the entrainment of information flow between sensing, signaling and motility.
    1. Developmental Biology

    Bicoid gradient formation and function in the Drosophila pre-syncytial blastoderm

    Zehra Ali-Murthy, Thomas B Kornberg
    The concentration gradient of Bicoid protein positions gene expression domains along the anterior/posterior axis of the Drosophila embryo during the cleavage, pre-syncytial blastoderm stages.
    1. Computational and Systems Biology
    2. Neuroscience

    Chemotaxis: In search of lost scent

    Ronald L Calabrese
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    1. Developmental Biology
    2. Neuroscience
    Pond snail illustration

    The Natural History of Model Organisms: The unlimited potential of the great pond snail, Lymnaea stagnalis

    István Fodor et al.
    The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.
    1. Cell Biology

    Mitochondrial Homeostasis: Auto-regulation in the powerhouse

    Helena M Viola, Livia C Hool
    Mitochondrial flashes have a central role in ensuring that ATP levels remain constant in heart cells.
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    1. Cell Biology
    2. Developmental Biology

    Germ Granules: All about the RNA after all

    Tatjana Trcek, Ruth Lehmann
    RNA molecules cause the proteins involved in the formation of germ granules to coalesce into liquid droplets.
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    1. Developmental Biology

    Development: Computing away the magic?

    Michael Levine
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