Improved 3D and 4D imaging of neurovascular processes across scales reveals new insights into eye disease mouse models and shows retinal vessels are significantly distorted using standard flat-mount confocal imaging.
Georg Kislinger, Gunar Fabig ... Martina Schifferer
An array tomography and electron tomography hybrid approach based on coated plastic tape as support advances ultrastructural analysis of biological phenomena that require cell- and tissue-level contextualization of the finest subcellular textures.
Axon repulsion in response to the midline repellent slit depends on an evolutionary conserved interaction between the Roundabout receptor and the wave regulatory complex.
Advanced genetics and imaging reveal wiring logic underlying the olfactory map organization in the developing fruit fly brain, and strategies employed by projection neurons to target dendrites to specific locations in a timely manner.
Munenori Ishibashi, Joyce Keung ... Stephen C Massey
Each cone terminal is electrically coupled to around 50 nearby rods, forming a switchable circuit, known as the secondary rod pathway, in which all gap junction channels participate.
Zhannetta V Gugel, Elizabeth G Maurais, Elizabeth J Hong
Chronic stimulation with odors at naturally occurring concentrations only mildly impacts early stages of olfactory processing, suggesting a need to re-interpret prevailing models of how chronic odor exposure affects olfactory function.
Steven R Sando, Nikhil Bhatla ... H Robert Horvitz
By driving the localized contraction of subcellular muscle regions, a single motor neuron reverses the flow of material in the Caenorhabditis elegans pharynx, a neuromuscular pump, converting feeding into spitting.
Kathryn M Tabor, Gregory D Marquart ... Harold A Burgess
A new resource of transgenic zebrafish lines facilitates precise targeting of neuronal cell-types within the brain, supported by online software for visualizing transgene expression patterns.
Cyanobacteria with chlorophyll f show substantial near-infrared radiation-driven photosynthesis and can play an important role for primary production in endolithic, intertidal habitats.