Browse the search results

Page 2 of 539
    1. Neuroscience
    2. Developmental Biology

    A novel optical microscope for imaging large embryos and tissue volumes with sub-cellular resolution throughout

    Gail McConnell, Johanna Trägårdh ... William Bradshaw Amos
    A new type of microscope reveals detail of organelles inside every cell in the entirety of an intact embryo or tissue region over 100 cubic millimeters in volume.
    1. Neuroscience

    A novel method (RIM-Deep) enhances imaging depth and resolution stability of deep-cleared brain tissue in inverted confocal microscopy

    Yisi Liu, Pu Wang ... Hongwei Zhou
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Monitoring ATP dynamics in electrically active white matter tracts

    Andrea Trevisiol, Aiman S Saab ... Johannes Hirrlinger
    ATP imaging of spiking optic nerve axons in real time reveals correlation between ATP levels and electrical activity as well as contribution of lactate metabolism to axonal ATP homeostasis.
    1. Immunology and Inflammation

    Intravital quantification reveals dynamic calcium concentration changes across B cell differentiation stages

    Carolin Ulbricht, Ruth Leben ... Anja E Hauser
    Heterogeneity in cytoplasmic calcium concentration alongside B cell activation and differentiation is measured intravitally using an interdisciplinary imaging approach and novel numerical analysis.
    1. Cell Biology
    2. Immunology and Inflammation

    A role for the centrosome in regulating the rate of neuronal efferocytosis by microglia in vivo

    Katrin Möller, Max Brambach ... Francesca Peri
    High-resolution imaging of microglia in zebrafish reveals a rate-limiting role for the centrosome in the engulfment of apoptotic neurons during brain development.
    1. Developmental Biology
    2. Plant Biology

    Live tracking of moving samples in confocal microscopy for vertically grown roots

    Daniel von Wangenheim, Robert Hauschild ... Jiří Friml
    A set of tools to image and track growing plant roots in optimized growing conditions within a vertical stage confocal microscope will open up new possibilities in research of root development.
    1. Developmental Biology
    2. Genetics and Genomics

    A timer gene network is spatially regulated by the terminal system in the Drosophila embryo

    Erik Clark, Margherita Battistara, Matthew A Benton
    A retracting gradient of the transcription factor Tailless spatiotemporally patterns the Drosophila tail region by modulating the intrinsic dynamics of a regulatory network involving the timer genes caudal, Dichaete, and odd-paired.
    1. Plant Biology

    A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level

    Vilde Olsson Lalun, Maike Breiden ... Melinka A Butenko
    A molecular investigation on the role of the peptide ligand inflorescence deficient in abscission (IDA) in regulating immunity and development during cell separation in Arabidopsis thaliana.
    1. Immunology and Inflammation

    Stochastic asymmetric repartition of lytic machinery in dividing CD8+ T cells generates heterogeneous killing behavior

    Fanny Lafouresse, Romain Jugele ... Salvatore Valitutti
    A fraction of human CD8+ T cells unequally partitions their lytic components during division, producing cells with heterogeneous killing capacities.
    1. Microbiology and Infectious Disease

    Antibiotic-induced accumulation of lipid II synergizes with antimicrobial fatty acids to eradicate bacterial populations

    Ashelyn E Sidders, Katarzyna M Kedziora ... Brian P Conlon
    Palmitoleic acid not only potentiates vancomycin killing of Gram-positive bacteria, but the insertion of palmitoleic acid into the membrane leads to the unexpected accumulation of membrane-bound cell wall precursors, representing a novel mechanism of action for unsaturated fatty acids.