44 results found
    1. Human Biology and Medicine
    2. Neuroscience

    Prognostication of chronic disorders of consciousness using brain functional networks and clinical characteristics

    Ming Song et al.
    Behavioral, pharmacological, optogenetic, electrophysiological and computational analyses suggest that the anterior dorsal striatum is a causal node in the network responsible for evidence accumulation.
    1. Cell Biology

    The adhesion function of the sodium channel beta subunit (β1) contributes to cardiac action potential propagation

    Rengasayee Veeraraghavan et al.
    Structural and functional investigations identify a structural unit for ephaptic coupling in the heart, and provide the mechanistic basis for a novel strategy for the treatment of arrhythmias.
    1. Neuroscience

    A transient cortical state with sleep-like sensory responses precedes emergence from general anesthesia in humans

    Laura D Lewis et al.
    Intracranial recordings of human brain activity during awakening from general anesthesia exhibit a brief brain state not seen during loss of consciousness, in which stimuli elicit large electrophysiological responses that resemble those seen in sleep.
    1. Neuroscience

    Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway

    Yalda Mohsenzadeh et al.
    Reducing visibility with higher image presentation rates increases recurrent processing demands along the visual processing pathway to resolve object recognition.
    1. Human Biology and Medicine
    2. Neuroscience

    Point of View: Predictive regulation and human design

    Peter Sterling
    Why does the human regulatory system, which evolution tuned for small satisfactions, now constantly demand 'more'?
    1. Neuroscience

    VEGF signaling regulates the fate of obstructed capillaries in mouse cortex

    Patrick Reeson et al.
    Mapping the fate of clogged brain capillaries reveals that VEGF signaling plays a critical role in dictating whether capillaries regain blood flow and persist or are pruned from the vascular tree.
    1. Human Biology and Medicine
    2. Neuroscience

    Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina

    Valentina Barrera et al.
    Clinical, clinicopathological and image data from Malawian children shows that sequestration in P. falciparum cerebral malaria is visible clinically in the eye as orange retinal vessels and is strongly associated with death.
    1. Neuroscience

    Pupillometry: Consciousness reflected in the eyes

    Woon Ju Park et al.
    People with higher autistic traits display stronger fluctuations in pupil size when presented with an optical illusion.
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    1. Neuroscience

    Associability-modulated loss learning is increased in posttraumatic stress disorder

    Vanessa M Brown et al.
    Veterans with PTSD show increased attention to a history of unexpected outcomes during loss learning, both as measured by computational model-derived behavioral parameters and in increased neural signaling in amygdala and insula.
    1. Neuroscience

    Neuropathological and transcriptomic characteristics of the aged brain

    Jeremy A Miller et al.
    High variability in neuropathology burden and interactions between dementia diagnosis and RNA quality present underappreciated complications when studying dementia in an aged population.

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